Publications associées à Gene–environment correlation

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Jacques Fellay, Christian Axel Wandall Thorball

Type 2 diabetes mellitus (T2DM) can be multifactorial where both genetics and environmental factors play a role. We aimed to investigate the use of polygenic risk scores (PRS) in the prediction of pre-transplant T2DM and post-transplant diabetes mellitus ( ...

Lausanne2023

Association of a Polygenic Risk Score With Osteoporosis in People Living With HIV: The Swiss HIV Cohort Study

Jacques Fellay, Christian Axel Wandall Thorball

An individual polygenic risk score was associated with osteoporosis in people living with HIV. The genetic effect was robust, as it persisted after multivariable adjustment for established traditional and HIV-related osteoporosis risk factors, including te ...

OXFORD UNIV PRESS INC2023

Synthesis of near-diffraction-free orbital-angular-momentum space-time wave packets having a controllable group velocity using a frequency comb

Tobias Kippenberg, Maxim Karpov, Zhe Zhao, Hao Song, Xinzhou Su

Novel forms of light beams carrying orbital angular momentum (OAM) have recently gained interest, especially due to some of their intriguing propagation features. Here, we experimentally demonstrate the generation of near-diffraction-free two-dimensional ( ...

Optica Publishing Group2022

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores

Jacques Fellay, Christian Axel Wandall Thorball

Background In people with human immunodeficiency virus (PWH), it is unknown whether genetic background associates with rapid progression of kidney dysfunction (ie, estimated glomerular filtration rate [eGFR] decrease of >5mL/min/1.73m(2) per year for >= 3 ...

OXFORD UNIV PRESS INC2021

Gene-by-environment modulation of lifespan and weight gain in the murine BXD family

Johan Auwerx, Maroun Bou Sleiman, Evan Graehl Williams, Pooja Jha

How lifespan and body weight vary as a function of diet and genetic differences is not well understood. Here we quantify the impact of differences in diet on lifespan in a genetically diverse family of female mice, split into matched isogenic cohorts fed a ...

NATURE PORTFOLIO2021

Spatial areas of genotype probability: Predicting the spatial distribution of adaptive genetic variants under future climatic conditions

Stéphane Joost, Oliver Michele Selmoni, Estelle Rochat

In a context of rapid global change, one of the key components for the survival of species is their genetic evolutionary potential for adaptation. Many methods have been developed to identify genetic variants underpinning adaptation to climate, but few too ...

WILEY2021

Contribution of Genetic Background and Data Collection on Adverse Events of Anti-human Immunodeficiency Virus (HIV) Drugs (D:A:D) Clinical Risk Score to Chronic Kidney Disease in Swiss HIV-infected Persons With Normal Baseline Estimated Glomerular Filtration Rate

Jacques Fellay, Christian Axel Wandall Thorball

Background. In human immunodeficiency virus (HIV), the relative contribution of genetic background, clinical risk factors, and antiretrovirals to chronic kidney disease (CKD) is unknown. Methods. We applied a case-control design and performed genome-wide g ...

OXFORD UNIV PRESS INC2020

Adapt or Perish: Evolutionary Rescue in a Gradually Deteriorating Environment

Anne-Florence Raphaëlle Bitbol, Loïc Marrec

We investigate the evolutionary rescue of a microbial population in a gradually deteriorating environment, through a combination of analytical calculations and stochastic simulations. We consider a population destined for extinction in the absence of mutan ...

2020

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Gene–environment correlation

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Association of a Polygenic Risk Score With Osteoporosis in People Living With HIV: The Swiss HIV Cohort Study

Inelastic Neutron Scattering for Néel Phase Excitation Spectrum of SrCu2(BO3)2

Selective elimination of enterovirus genotypes by activated sludge and chlorination

Synthesis of near-diffraction-free orbital-angular-momentum space-time wave packets having a controllable group velocity using a frequency comb

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores

Gene-by-environment modulation of lifespan and weight gain in the murine BXD family

Spatial areas of genotype probability: Predicting the spatial distribution of adaptive genetic variants under future climatic conditions

Contribution of Genetic Background and Data Collection on Adverse Events of Anti-human Immunodeficiency Virus (HIV) Drugs (D:A:D) Clinical Risk Score to Chronic Kidney Disease in Swiss HIV-infected Persons With Normal Baseline Estimated Glomerular Filtration Rate

Adapt or Perish: Evolutionary Rescue in a Gradually Deteriorating Environment

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Chattez avec Graph Search

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Inelastic Neutron Scattering for Néel Phase Excitation Spectrum of SrCu2(BO3)2

Gene-by-environment modulation of lifespan and weight gain in the murine BXD family

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores

Association of a Polygenic Risk Score With Osteoporosis in People Living With HIV: The Swiss HIV Cohort Study

Spatial areas of genotype probability: Predicting the spatial distribution of adaptive genetic variants under future climatic conditions

Adapt or Perish: Evolutionary Rescue in a Gradually Deteriorating Environment

Contribution of Genetic Background and Data Collection on Adverse Events of Anti-human Immunodeficiency Virus (HIV) Drugs (D:A:D) Clinical Risk Score to Chronic Kidney Disease in Swiss HIV-infected Persons With Normal Baseline Estimated Glomerular Filtration Rate

Selective elimination of enterovirus genotypes by activated sludge and chlorination

Synthesis of near-diffraction-free orbital-angular-momentum space-time wave packets having a controllable group velocity using a frequency comb