Concept
Autoinducer
Publications associées (25)
Tracking the cargo of extracellular symbionts into host tissues with correlated electron microscopy and nanoscale secondary ion mass spectrometry imaging
Anders Meibom, Stéphane Laurent Escrig, Stéphanie Kéren Cohen
Extracellular bacterial symbionts communicate biochemically with their hosts to establish niches that foster the partnership. Using quantitative ion microprobe isotopic imaging (nanoscale secondary ion mass spectrometry [NanoSIMS]), we surveyed localizatio ...
WILEY2020Insights into flagellar function and mechanism from the squid-vibrio symbiosis
Flagella are essential and multifunctional nanomachines that not only move symbionts towards their tissue colonization site, but also play multiple roles in communicating with the host. Thus, untangling the activities of flagella in reaching, interacting, ...
2019Bacterial type VI secretion system facilitates niche domination
Melanie Blokesch, Natalia Carolina Drebes Dorr
Over the last few decades humanity has experienced a series of tremendous technological advances, especially in the realm of basic science. A plethora of new approaches has allowed us to appreciate life in previously unimaginable detail, prompting the real ...
2018Visualizing chemical transport from extracellular symbionts into squid host tissues using NanoSIMS
Chemical communication is the basis of host-microbe interaction. Insights into this communication will provide a deeper understanding of the mechanisms that govern these complex associations, in beneficial as well as pathogenic contexts. In this dissertati ...
EPFL2017Bioluminescent Antibodies for Point-of-Care Diagnostics
Kai Johnsson, Rudolf Griss, Alberto Schena, Qiuliyang Yu, Lin Xue
We introduce a general method to transform antibodies into ratiometric, bioluminescent sensor proteins for the no-wash quantification of analytes. Our approach is based on the genetic fusion of antibody fragments to NanoLuc luciferase and SNAP-tag, the lat ...
2017Halide removal from waters by silver nanoparticles and hydrogen peroxide
The objective of this study was to remove halides from waters by silver nanoparticles (AgNPs) and hydrogen peroxide (H2O2). The experimental parameters were optimized and the mechanism involved was also determined. The AgNP/H2O2 process proved efficacious ...
Elsevier2017Tracking the signaling cargo of extracellular symbionts into host tissues
Anders Meibom, Julia Marie Jeanne Yvonne Bodin, Stéphanie Kéren Cohen
Animal-microbe symbioses are fundamental to animal physiology but the precise nature of molecular exchange between partners remains largely elusive. The mutualistic association between the Hawaiian bobtail squid, Euprymna scolopes and its luminous bacteriu ...
2016Tracking the signaling cargo of extracellular symbionts into host tissues
Anders Meibom, Julia Marie Jeanne Yvonne Bodin, Stéphanie Kéren Cohen
Animal-microbe symbioses are fundamental to animal physiology but how and where bacteria interact with their host, remain largely elusive. The mutualistic association between the Hawaiian bobtail squid, Euprymna scolopes and its luminous bacterium Vibrio f ...
2016Regulatory elements involved in the expression of competence genes in naturally transformable Vibrio cholerae
Melanie Blokesch, Mirella Lo Scrudato
BackgroundThe human pathogen Vibrio cholerae normally enters the developmental program of natural competence for transformation after colonizing chitinous surfaces. Natural competence is regulated by at least three pathways in this organism: chitin sensing ...
BioMed Central2014Bioluminescent sensor proteins for point-of-care therapeutic drug monitoring
Kai Johnsson, Luc Reymond, Luc Patiny, Rudolf Griss, Alberto Schena
For many drugs, finding the balance between efficacy and toxicity requires monitoring their concentrations in the patient's blood. Quantifying drug levels at the bedside or at home would have advantages in terms of therapeutic outcome and convenience, but ...
Nature Publishing Group2014