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Domestication of livestock species and a long history of migrations, selection and adaptation have created an enormous variety of breeds. Conservation of these genetic resources relies on demographic characterization, recording of production environments a ...
The metabolic impact of the common peroxisome proliferator-activated receptor gamma isoform 2 (PPARgamma2) variant Pro12Ala in human populations has been widely debated. We demonstrate, using a Pro12Ala knockin model, that on chow diet, Ala/Ala mice are le ...
Reductive evolution and massive pseudogene formation have shaped the 3.31-Mb genome of Mycobacterium leprae, an unculturable obligate pathogen that causes leprosy in humans. The complete genome sequence of M. leprae strain Br4923 from Brazil was obtained b ...
This paper synthesizes recent works at the interface of hydrology, geomorphology, and ecology under an integrated framework of analysis with an aim for a general theory. It addresses a wide range of related topics, including biodiversity of freshwater fish ...
Leprosy, a chronic human disease with potentially debilitating neurological consequences, results from infection with Mycobacterium leprae. This unculturable pathogen has undergone extensive reductive evolution, with half of its genome now occupied by pseu ...
Information access in meeting recordings can be assisted by meeting browsers, or can be fully automated following a question-answering (QA) approach. An information access task is defined, aiming at discriminating true vs. false parallel statements about f ...
A discrete, structured metapopulation model is coupled with the strictly hierarchical competition-colonization trade-off model, in which competitively superior species have lower fecundity rates and thus lower colonizing ability, to study the resulting bio ...
As the focus of human genetics shifts from Mendelian traits to complex diseases, a sophisticated genetic tool kit—with space for genetics (classical, molecular, statistical, and quantitative), metabolics, proteomics, bioinformatics, and mathematics—is requ ...
Information access in meeting recordings can be assisted by meeting browsers, or can be fully automated following a question-answering (QA) approach. An information access task is defined, aiming at discriminating true vs. false parallel statements about f ...
We present new polymeric amphiphiles derived from N-acryloyl derivatives of the cyclic secondary amines: morpholine, piperidine, and azocane polymerized by reversible addition -fragmentation transfer (RAFT) polymerization. Both homopolymerization and block ...