Concept

Retard de croissance intra-utérin

Publications associées (47)

Bidirectional Transfer Study of Polystyrene Nanoparticles across the Placental Barrier in an ex Vivo Human Placental Perfusion Model

BACKGROUND: Nanoparticle exposure in utero might not be a major concern yet, but it could become more important with the increasing application of nanomaterials in consumer and medical products. Several epidemiologic and invitro studies have shown that nan ...

Nat Inst of Environ Health Sciences / The National Institute of Environmental Health Sciences (NIEHS)2015

Longitudinal analysis of brain network reorganization in preterm IUGR children at 1, 6 and 9 years-old

Jean-Philippe Thiran, Elda Fischi Gomez

Intrauterine Growth Restriction (IUGR) due to placental insufficiency affects 5-10% of all pregnancies and it is associated with a wide range of short and long-term neurodevelopmental disorders. Different approaches have been considered to understand IUGR ...

2014

Protective effects of maternal nutritional supplementation with lactoferrin on growth and brain metabolism

Rolf Gruetter, Yohan Van de Looij, Sylviane Métairon

Background:Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementati ...

Nature Publishing Group2014

Definition and quantification of acute inflammatory white matter injury in the immature brain by MRI/MRS at high magnetic field

Rolf Gruetter, Nicolas Kunz

Background: Intrauterine growth restriction (IUGR) is a major risk factor for both perinatal and long-term morbidity. Bovine lactoferrin (bLf) is a major milk glycoprotein considered as a pleiotropic functional nutrient. The impact of maternal supplementat ...

Nature Publishing Group2014

Brain Connections Associated With Socio-Cognitive Skills in Preterm and Low Birth Weight School Age Children

Jean-Philippe Thiran, Elda Fischi Gomez, Patric Hagmann, Djalel Eddine Meskaldji, François Lazeyras

Identification of neuroimaging biomarkers following extreme prematurity (EP) and intrauterine growth restriction (IUGR) is crucial for understanding their cognitive and behavioral impairments at school age ...

2014

The Channel-Activating Protease CAP1/Prss8 Is Required for Placental Labyrinth Maturation

Simona Frateschi, Friedrich Beermann, Roch-Philippe Charles, Aline Dousse

The serine protease CAP1/Prss8 is crucial for skin barrier function, lung alveolar fluid clearance and has been unveiled as diagnostic marker for specific cancer types. Here, we show that a constitutive knockout of CAP1/Prss8 leads to embryonic lethality. ...

Public Library of Science2013

Regional changes of cortical thickness and cortical surface in children born prematurely and children born with intrauterine growth restriction at school age

Elda Fischi Gomez, Laura Ioana Gui, François Lazeyras

Premature birth and the early exposure to environmental sensory information influence the cascade of histogenetic events that occur during the development of human telencephalon. The prenatal establishment of the genetically driven number and size of the e ...

2013

Liver receptor homolog-1 is essential for pregnancy

Kristina Schoonjans

Successful pregnancy requires coordination of an array of signals and factors from multiple tissues. One such element, liver receptor homolog-1 (Lrh-1), is an orphan nuclear receptor that regulates metabolism and hormone synthesis(1). It is strongly expres ...

Nature Publishing Group2013

Rapid Intrahost Evolution of Human Cytomegalovirus Is Shaped by Demography and Positive Selection

Jeffrey David Jensen

Populations of human cytomegalovirus (HCMV), a large DNA virus, are highly polymorphic in patient samples, which may allow for rapid evolution within human hosts. To understand HCMV evolution, longitudinally sampled genomic populations from the urine and p ...

Public Library of Science2013

Proteolytic Processing Regulates Placental Growth Factor Activities

Jeffrey Alan Hubbell, Stéphanie Elisabeth Metzger, Martin Ehrbar, Manuel Koch

Placental growth factor (PlGF) is a critical mediator of blood vessel formation, yet mechanisms of its action and regulation are incompletely understood. Here we demonstrate that proteolytic processing regulates the biological activity of PlGF. Specificall ...

Amer Soc Biochemistry Molecular Biology Inc2013

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