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Pentameric ligand-gated ion channels from the Cys-loop family mediate fast chemo-electrical transduction, but the mechanisms of ion permeation and gating of these membrane proteins remain elusive. Here we present the X-ray structure at 2.9 A resolution of ...
Multiplexing rate and diversity impose a fundamental trade-off in wireless communications. This tradeoff was investigated for Inter-symbol Interference (ISI) channels in [8]. A different point of view was explored in [2], [5], [6] where high rate codes wer ...
Biphasic electrospray ionization (BESI) mass spectrometry is achieved by using a dual-channel microsprayer, where channels filled with different immiscible phases meet at the Taylor cone. Two types of interfacial complexation reactions have been studied: t ...
The Japan Society of Analytical Chemistry / The Japan Society for Analytical Chemistry2008
The nicotinic acetylcholine receptor (nAChR) is a ligand-gated ion channel that switches upon activation from a closed state to a full conducting state. We found that the mutation delta S268K, located at 12' position of the second transmembrane domain of t ...
The Voltage Dependent Anion Channel (VDAC) is the most abundant protein in the outer membrane of mitochondria. This strategic localization puts it at the heart of a great number of phenomena. Its recent implication in apoptosis is an example of the major i ...
Burnashev in 1976 gave an exact expression for the reliability function of a discrete memoryless channel (DMC) with noiseless feedback. A coding scheme that achieves this exponent needs, in general, to know the statistics of the channel. Suppose now that t ...
On-column conductivity detection in capillary-chip electrophoresis was achieved by actively coupling the high electric field with two sensing electrodes connected to the main capillary channel through two side detection channels. The principle of this conc ...
Rate and diversity impose a fundamental trade-off in communications. This tradeoff was investigated for Intersymbol Interference (ISI) channels in [7]. A different point of view was explored in [4] where high-rate codes were designed so that they have a hi ...
A channel model for channels with unknown state and partial state information available causally at the decoder is proposed. The model is based on arbitrarily varying channels (AVCs), and the partial state information is characterized by allowing the decod ...
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Nicotinic acetylcholine receptors are heteropentameric ion channels that open upon activation to a single conducting state. The second transmembrane segments of each subunit were identified as channel-forming elements, but their respective contribution in ...