Concept

In vivo

Publications associées (135)

Microfluidic and micromechanical in vivo studies of Caenorhabditis elegans

Caenorhabditis elegans is one of the most attractive model organisms in biomedical research for understanding human diseases and for drug testing at a whole-organism level, since many biological pathways and genes have been conserved between itself and hum ...

EPFL2019

Azacyanine dyes and use thereof

Riccardo Sinisi, Elena Goun, Alma Rosa Morales Morales

The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are de ...

2019

Azacyanine dyes and use thereof

Riccardo Sinisi, Elena Goun, Alma Rosa Morales Morales

2019

Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach

Bruno Lemaitre, Camilla Carla Alma Ceroni, Mark Austin Hanson, Anna Dostalova

Antimicrobial peptides (AMPs) are host-encoded antibiotics that combat invading microorganisms. These short, cationic peptides have been implicated in many biological processes, primarily involving innate immunity. In vitro studies have shown AMPs kill bac ...

Cambridge University Press2019

Virucidal nanomaterials against influenza

Özgün Kocabiyik

Influenza affects millions of people in all parts of the world. The fact that influenza virus can spread through air increases the chance of influenza outbreaks. There are 3 to 5 million severe cases of influenza resulting in 290,000 to 650,000 deaths ever ...

EPFL2019

Fast model-based T-2 mapping using SAR-reduced simultaneous multislice excitation

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, José Pedro Rebelo Ferreira Marques

Purpose To obtain whole-brain high-resolution T-2 maps in 2 minutes by combining simultaneous multislice excitation and low-power PINS (power independent of number of slices) refocusing pulses with undersampling and a model-based reconstruction. Methods A ...

WILEY2019

In vivo imaging with microsphere-based super-resolution microscopy

Martinus Gijs, Gergely Huszka, Roger Philippe Krenger

Employing dielectric microspheres in a standard microscope setup is an alternative to image sub-diffraction features optically, however this method suffers from a limited field-of-view. Here, we show our microsphere-based optical super-resolution microscop ...

IEEE2018

An ecotoxicological view on neurotoxicity assessment

Wolfgang Schulz

The numbers of potential neurotoxicants in the environment are raising and pose a great risk for humans and the environment. Currently neurotoxicity assessment is mostly performed to predict and prevent harm to human populations. Despite all the efforts in ...

SPRINGEROPEN2018

Calcium phosphate formation on titanium-based surfaces: bioactivity evaluated by in vitro methods

Weitian Zhao

The prediction of implant behaviors in vivo by the use of easy-to-perform in vitro methods is of great interest in biomaterials research. In the field of bone implants, it is commonly accepted that a spontaneous formation of a hydroxyapatite (HA) layer on ...

EPFL2018

Peptide-based coatings for flexible implantable neural interfaces

Silvestro Micera

In the last decade, the use of flexible biosensors for neuroprosthetic and translational applications has widely increased. Among them, the polyimide (PI)-based thin-film electrodes got a large popularity. However, the usability of these devices is still h ...

2018

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