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The main subject of the present thesis is the experimental study of the scaling properties of DNA knots of different complexities by tapping mode atomic force microscopy (AFM) in air. Homo- or heterogeneous mixture of DNA knot types were deposited onto mic ...
Minimally Invasive Surgery (MIS) represents one of the major progresses in surgery in the last decade. In general, it is based on the application of small body-cuts through which instruments are inserted into the patient's body allowing the surgeon to carr ...
Real-time simulation of thread and knot-tying with visual and force feedback is an essential part of virtual reality laparoscopic training. This paper presents a physics-based thread simulator that enables realistic knot tying at haptic rendering rate. The ...
The distance from self-intersection of a (smooth and either closed or infinite) curve q in three dimensions can be characterised via the global radius of curvature at q(s), which is defined as the smallest possible radius amongst all circles passing throug ...
The scaling properties of DNA knots of different complexities were studied by atomic force microscope. Following two different protocols DNA knots are adsorbed onto a mica surface in regimes of (i) strong binding, that induces a kinetic trapping of the thr ...
Real-time simulation of knot-tying with visual and force feedback is essential to VR surgery training. We present a physics-based simulator that enables realistic knot tying at haptic speed. The virtual thread obeys Newton's laws and behaves naturally. The ...
Gel electrophoresis can be used to separate nicked circular DNA molecules of equal length but forming different knot types. At low electric fields, complex knots drift faster than simpler knots. However, at high electric field the opposite is the case and ...