Concept
Récepteur GABAA
Publications associées (43)
Robust gamma-aminobutyric acid and energy metabolism measurements by proton and phosphorus magnetic resonance spectroscopy and fingerprinting
Magnetic resonance spectroscopy (MRS) is the only technique that can detect endogenous metabolites directly and non-invasively in vivo. It allows to identify different metabolites and analyze the dynamic neurochemical processes in the brain, skeletal muscl ...
EPFL2023Colchicine stimulates browning via antagonism of GABA receptor B and agonism of? 3-adrenergic receptor in 3T3-L1 white adipocytes
Colchicine has been used for therapeutic purposes and has attracted considerable attention because of its association with tubulin and the inhibition of small tubular polymerization. Although several studies have examined the possible preventive role of co ...
ELSEVIER IRELAND LTD2022Lower glutamate and GABA levels in auditory cortex of tinnitus patients: a 2D-JPRESS MR spectroscopy study
Thorsten Kleinjung, Patrick Karl Alois Neff
We performed magnetic resonance spectroscopy (MRS) on healthy individuals with tinnitus and no hearing loss (n = 16) vs. a matched control group (n = 17) to further elucidate the role of excitatory and inhibitory neurotransmitters in tinnitus. Two-dimensio ...
2022Cell-type-specific nicotinic input disinhibits mouse barrel cortex during active sensing
Carl Petersen, Sylvain Crochet, Célia Roxane Gasselin, Benoît Hohl
Fast synaptic transmission relies upon the activation of ionotropic receptors by neurotransmitter release to evoke postsynaptic potentials. Glutamate and GABA play dominant roles in driving highly dynamic activity in synaptically connected neuronal circuit ...
CELL PRESS2021GABA-mediated tonic inhibition differentially modulates gain in functional subtypes of cortical interneurons
Sean Lewis Hill, Christian Andreas Rössert, Bas-Jan Zandt, Steven Petrou
The binding of GABA (gamma-aminobutyric acid) to extrasynaptic GABA(A) receptors generates tonic inhibition that acts as a powerful modulator of cortical network activity. Despite GABA being present throughout the extracellular space of the brain, previous ...
NATL ACAD SCIENCES2020GABA A receptors in the ventral tegmental area control the outcome of a social competition in rats
Maria del Carmen Sandi Perez, Michael van der Kooij, Ioannis Zalachoras
Social dominance can be attained through social competitions. Recent work in both humans and rodents has identified trait anxiety as a crucial predictor of social competitiveness. In addition, the anxiolytic GABAA positive modulator, diazepam, injected eit ...
2018