Concept
Choline
Publications associées (32)
Relief of ParB autoinhibition by parS DNA catalysis and recycling of ParB by CTP hydrolysis promote bacterial centromere assembly
Paolo De Los Rios, Stefano Zamuner
Three-component ParABS systems are widely distributed factors for plasmid partitioning and chromosome segregation in bacteria. ParB acts as adaptor protein between the 16-base pair centromeric parS DNA sequences and the DNA segregation proteins ParA and Sm ...
AMER ASSOC ADVANCEMENT SCIENCE2021Tailored extracellular electron transfer pathways enhance the electroactivity of Escherichia coli
Ardemis Anoush Boghossian, Melania Reggente, Mohammed Mouhib, Nils Schürgers, Lin Li
Extracellular electron transfer (EET) engineering in Escherichia coli holds great potential for bioremediation, energy and electrosynthesis applications fueled by readily available organic substrates. Due to its vast metabolic capabilities and availability ...
2021Self-organization of parS centromeres by the ParB CTP hydrolase
Paolo De Los Rios, Stefano Zamuner
ParABS systems facilitate chromosome segregation and plasmid partitioning in bacteria and archaea. ParB protein binds centromeric parS DNA sequences and spreads to flanking DNA. We show that ParB is an enzyme that hydrolyzes cytidine triphosphate (CTP) to ...
2019Diffusion behavior of cerebral metabolites of congenital portal systemic shunt mice assessed noninvasively by diffusion-weighted H-1 magnetic resonance spectroscopy
Hongxia Lei, Nicolas Kunz, Masoumeh Dehghani Moghadam
Diffusion-weighted H-1-MRS (DW-MRS) allows for noninvasive investigation of the cellular compartmentalization of cerebral metabolites. DW-MRS applied to the congenital portal systemic shunt (PSS) mouse brain may provide specific insight into alterations of ...
2019Mild Neonatal Brain Hypoxia-Ischemia in Very Immature Rats Causes Long-Term Behavioral and Cerebellar Abnormalities at Adulthood
Hongxia Lei, Yohan Van de Looij
Systemic hypoxia-ischemia (HI) often occurs during preterm birth in human. HI induces injuries to hinder brain cells mainly in the ipsilateral forebrain structures. Such HI injuries may cause lifelong disturbances in the distant regions, such as the contra ...
2019Sphingolipid metabolic flow controls phosphoinositide turnover at the trans ‐Golgi network
Giovanni D'Angelo, Howard Riezman, Riccardo Rizzo
Sphingolipids are membrane lipids globally required for eukaryotic life. The sphingolipid content varies among endomembranes with pre- and post-Golgi compartments being poor and rich in sphingolipids, respectively. Due to this different sphingolipid conten ...
2017