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In this thesis, we give new approximation algorithms for some NP-hard problems arising in resource allocation and network design. As a resource allocation problem, we study the Santa Claus problem (also known as the MaxMin Fair Allocation problem) in which ...
The lattice Green's function method (LGFM) is the discrete counterpart of the continuum boundary element method and is a natural approach for solving intrinsically discrete solid mechanics problems that arise in atomistic-continuum coupling methods. Here, ...
Tris-(2-carboxyethyl)phosphine (TCEP) linked to agarose beads is widely used for reducing disulfide bridges in proteins and peptides. The immobilization of TCEP on beads allows efficient removal after reduction to prevent its reaction with alkylating reage ...
We show that Cutting Planes (CP) proofs are hard to find: Given an unsatisfiable formula F, It is -hard to find a CP refutation of F in time polynomial in the length of the shortest such refutation; and unless Gap-Hitting-Set admits a nontrivial algorithm, ...
Submodular functions are a widely studied topic in theoretical computer science. They have found several applications both theoretical and practical in the fields of economics, combinatorial optimization and machine learning. More recently, there have also ...
A motif is a frequently occurring subgraph of a given directed or undirected graph G (Milo et al.). Motifs capture higher order organizational structure of G beyond edge relationships, and, therefore, have found wide applications such as in graph clusterin ...
We relate discrepancy theory with the classic scheduling problems of minimizing max flow time and total flow time on unrelated machines. Specifically, we give a general reduction that allows us to transfer discrepancy bounds in the prefix Beck-Fiala (bound ...
Given two elliptic curves and the degree of an isogeny between them, finding the isogeny is believed to be a difficult problem—upon which rests the security of nearly any isogeny-based scheme. If, however, to the data above we add information about the beh ...
This paper addresses the complexity reduction of stochastic homogenization of a class of random materials for a stationary diffusion equation. A cost-efficient approximation of the correctors is obtained using a method designed to exploit quasi-periodicity ...
We study the computational complexity of the optimal transport problem that evaluates the Wasser- stein distance between the distributions of two K-dimensional discrete random vectors. The best known algorithms for this problem run in polynomial time in th ...