Concept

Porosome

Publications associées (32)

Water as a contrast agent for imaging interfacial structure and ion transport in giant vesicles

Hydrated lipid bilayer membranes and their asymmetry play a fundamental role in living cells by maintaining and regulating concentration gradients between cells, their environment, and their compartments. They achieve this not only through various channels ...

EPFL2022

Crystallization of Size-Selective Nanopores in Graphene for Gas Separation

Nanoporous single-layer graphene (N-SLG) membranes, owing to their single-atom thinness, have the potential to exceed the permeance and selectivity limits of gas separation membranes. However, two key issues in the top-down N-SLG synthesis need to be addre ...

EPFL2022

Mass transport of water vapor and ions from Å-scale graphene nanopores

Wan-Chi Lee

Hydrodynamics at the nanoscale involves both fundamental study and application of fluid and mass transport phenomena in nanometer-sized confinements. Nanopores in single-layer graphene can be highly attractive for exploring the molecular transport of gas a ...

EPFL2022

Calcium-triggered fusion of lipid membranes is enabled by amphiphilic nanoparticles

Francesco Stellacci, Ye Yang, Ahmet Bekdemir, Zekiye Pelin Güven

Lipid membrane fusion is an essential process for a number of critical biological functions. The overall process is thermodynamically favorable but faces multiple kinetic barriers along the way. Inspired by nature's engineered proteins such as SNAP recepto ...

NATL ACAD SCIENCES2020

Calcium-Mediated Liposome Fusion to Engineer Giant Lipid Vesicles with Cytosolic Proteins and Reconstituted Mammalian Proteins

Leo Scheller

Giant unilamellar lipid vesicles (GUVs) are widely used as model membrane systems and provide an excellent basis to construct artificial cells. To construct more sophisticated artificial cells, proteins-in particular membrane proteins-need to be incorporat ...

2020

Microscopic Detection Analysis of Single Molecules in MoS2 Membrane Nanopores

Aleksandra Radenovic, Michael Graf

A systematic microscopic analysis of the various resistive effects involved in the electronic detection of single biomolecules in a nanopore of a MoS2 nanoribbon is presented. The variations of the transverse electronic current along the two-dimensional (2 ...

2020

Centimeter-scale gas-sieving nanoporous single-layer graphene membrane

Kumar Varoon Agrawal, Mostapha Dakhchoune, Shiqi Huang, Guangwei He, Wan-Chi Lee

High-permeance, molecular-sieving, nanoporous single-layer graphene (NSLG) membranes are highly promising for gas separation. However, the formation of cracks during the transfer of NSLG to a low-cost porous support is difficult to avoid. These cracks are ...

2020

High-permeance polymer-functionalized single-layer graphene membranes that surpass the postcombustion carbon capture target

Emad Oveisi, Kumar Varoon Agrawal, Mounir Driss Mensi, Luis Francisco Villalobos Vazquez de la Parra, Shiqi Huang, Guangwei He, Jing Zhao

Membrane-based postcombustion carbon capture can reduce the capture penalty in comparison to absorbent-based separation. To realize this, high-performance membranes are urgently needed with a CO2 permeance exceeding 1000 gas permeation units or GPU, and a ...

2019

Generation of Native, Untagged Huntingtin Exon1 Monomer and Fibrils Using a SUMO Fusion Strategy

Hilal Lashuel, Jonathan Jean-Pierre Ricci, Anass Chiki, Andreas Reif

Huntington’s Disease (HD) is an inherited fatal neurodegenerative disease caused by a CAG expansion (36) in the first exon of the HD gene, resulting in the expression of the Huntingtin protein (Htt) or N-terminal fragments thereof with an expanded polygl ...

2018

Nano Secondary Ion Mass Spectrometry Imaging of Dopamine Distribution Across Nanometer Vesicles

Anders Meibom, Anna Larsson

We report an approach to spatially resolve the content across nanometer neuroendocrine vesicles in nerve-like cells by correlating super high-resolution mass spectrometry imaging, NanoSIMS, with transmission electron microscopy (TEM). Furthermore, intracel ...

American Chemical Society2016

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