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Biomechanical forces, such as fluid shear stress, govern multiple aspects of endothelial cell biology. In blood vessels, disturbed flow is associated with vascular diseases, such as atherosclerosis, and promotes endothelial cell proliferation and apoptosis ...
A new hearing therapy based on direct acoustic cochlear stimulation was developed for the treatment of severe to profound mixed hearing loss. The device efficacy was validated in an initial clinical trial with four patients. This semi-implantable investiga ...
Institute of Electrical and Electronics Engineers2011
Sensorineural hearing loss is the most common type of hearing loss worldwide, yet the underlying cause is typically unknown because the inner ear cannot be biopsied today without destroying hearing, and intracochlear cells have not been imaged with resolut ...
A new hearing therapy called Direct Acoustical Cochlear Stimulation (DACS) was developed and validated in a first clinical trial with four patients. The key component of this therapy based on an implantable hearing device is a micro-actuator that is implan ...
The extracellular potential of excitable and nonexcitable cells with respect to ground is ∼0 mV. One of the known exceptions in mammals is the cochlear duct, where the potential is ∼80-100 mV, called the endocochlear potential (EP). The EP serves as the "b ...
Tinnitus, the chronic perception of ringing or other phantom sounds, is typically associated with hearing loss. The reduction of auditory input that conveys to auditory cortex leads to the changes in the balance of excitatory and inhibitory activation of t ...
A new hearing therapy called Direct Acoustical Cochlear Stimulation (DACS) was developed and validated in a first clinical trial with four patients. The key component of this therapy based on an implantable hearing device is a micro-actuator that is implan ...
Nowadays, hearing impaired people can be treated with a multitude of different devices and surgical interventions that are selected in function of the type and degree of hearing loss of the patient. These known therapies cover the major part of possible he ...
Here we describe a method for measuring tonotopic maps and estimating bandwidth for voxels in human primary auditory cortex (PAC) using a modification of the population Receptive Field (pRF) model, developed for retinotopic mapping in visual cortex by Dumo ...
Tinnitus, the chronic perception of ringing or other phantom sounds, is typically associated with hearing loss. Recent studies in mouse models have alleviated tinnitus symptom by reversing plastic reorganization observed in the tonotopic maps of primary au ...