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Publications associées (337)

Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone

Ubiquitin-specific protease 19 (USP19) is one of the deubiquitinating enzymes (DUBs) involved in regulating the ubiquitination status of substrate proteins. There are two major isoforms of USP19 with distinct C-termini; the USP19_a isoform has a transmembr ...

Public Library of Science2016

Structure of fully protonated proteins by proton-detected magic-angle spinning NMR

David Lyndon Emsley, Andrea Bertarello

Protein structure determination by proton-detected magic-angle spinning (MAS) NMR has focused on highly deuterated samples, in which only a small number of protons are introduced and observation of signals from side chains is extremely limited. Here, we sh ...

National Academy of Sciences2016

Simultaneous EEG-fMRI at ultra-high field for the study of human brain function

João Pedro Forjaco Jorge

Scalp electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have highly complementary domains, and their combination has been actively sought within neuroscience research. The important gains in fMRI sensitivity achieved with higher ...

EPFL2016

Tesla: An application for real-time data analysis in High Energy Physics

Ilya Komarov, Gerhard Raven

Upgrades to the LHCb computing infrastructure in the first long shutdown of the LHC have allowed for high quality decay information to be calculated by the software trigger making a separate offline event reconstruction unnecessary. Furthermore, the storag ...

Elsevier Science Bv2016

When to stop? - Towards universal instructional policies

The adaptivity of intelligent tutoring systems relies on the accuracy of the student model and the design of the instructional policy. Recently an instructional policy has been presented that is compatible with all common student models. In this work we pr ...

Association for Computing Machinery2016

Toward Semantic Sensor Data Archives on the Web

Karl Aberer, Jean Paul Calbimonte Perez

Sensor datasets on the Web are becoming increasingly available, and there is a need for making them discoverable and accessible, so that they can be reused despite their heterogeneity. While RDF and Linked Data provide fundamental principles for sharing da ...

2016

Model-free computation of ultra-short-term prediction intervals of solar irradiance

Jean-Yves Le Boudec, Mario Paolone, Dimitri Torregrossa

We propose an ultra-short-term dynamic interval predictor (DIP) of solar irradiance. Our DIP relies on experimentally observed correlations between the derivative of the solar irradiance and the forecast error in the next time-step. The main originalities ...

Pergamon-Elsevier Science Ltd2016

Fracture toughness measurement in fused quartz using triangular chevron-notched micro-cantilevers

Andreas Mortensen, Goran Zagar, Martin Guillermo Mueller, Václav Pejchal, Lionel Michelet

We extend to flat surfaces the fracture toughness method presented in Acts Materialia vol. 86 (2015) p.385 and measure in this manner the fracture toughness of fused quartz. Tests give 0.67 +/- 0.01 MPa m(1/2) which agrees with earlier microscopic and macr ...

Elsevier2016

Managing Quality of Crowdsourced Data

Thành Tâm Nguyên

The Web is the central medium for discovering knowledge via various sources such as blogs, social media, and wikis. It facilitates access to contents provided by a large number of users, regardless of their geographical locations or cultural backgrounds. S ...

2015

Crowdsourcing Microdata for Cost-Effective and Reliable Lexicography

Martin Benjamin

Lexicography has long faced the challenge of having too few specialists to document too many words in too many languages with too many linguistic features. Great dictionaries are invariably the product of many person-years of labor, whether the lifetime wo ...

2015

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