Concept

Voltage-gated calcium channel

Publications associées (210)

Ligand binding transmits conformational changes across the membrane-spanning region to the intracellular side of the 5-HT3 serotonin receptor

Horst Vogel, Horst Pick, Cédric Deluz, Erwin Ilegems

Conformational changes of channel activation: Five enhanced green fluorescent protein (EGFP) mols. (green cylinders) were integrated into the intracellular part of the homopentameric ionotropic 5-HT3 receptor. This allowed the detection of extracellular bi ...

2005

Calcium dynamics and vasomotion in rat mesenteric arteries

Nikolaos Stergiopoulos, Jean-Jacques Meister, Jean-Louis Bény, Alexander Schuster, Mathieu Lamboley

Smooth muscle cell calcium dynamics and diameter were measured in intact pressurized rat mesenteric artery segments during vasoconstriction and vasomotion. Arteries showed a certain norepinephrine (NE) threshold (0.3-0.4 microM) for the onset of vasomotion ...

2004

Polyelectrolyte-modified short microchannel for cation separation

Hubert Girault, Christophe Roussel, Xiaoxia Bai

Three alkali cations, potassium, sodium, and lithium, have been separated within 15 s in a 1 cm long polymer microchip. The separation microchannel is modified by a polycation, poly(allylammonium chloride), which makes the channel surfaces positively charg ...

2004

Correlation maps allow neuronal electrical properties to be predicted from single-cell gene expression profiles in rat neocortex

Henry Markram

The computational power of the neocortex arises from interactions of multiple neurons, which display a wide range of electrical properties. The gene expression profiles underlying this phenotypic diversity are unknown. To explore this relationship, we comb ...

Oxford University Press2004

High voltage devices for standard MOS technologies

Costin Anghel

This work reports on the analysis of high voltage lateral devices. Two different architectures, self-aligned LDMOS and non-self-aligned XDMOS are presented and used in this work. For the separation of the physical effects that take place inside the HV devi ...

EPFL2004

Plastic micropumps using ferrofluid and magnetic membrane actuation

Martinus Gijs, Christophe Yamahata

This paper presents a simple and low-cost prototyping technology for the realization of integrated micropumps in polymethylmethacrylate (PMMA). The three-dimensional (3D) micropumps consist of stacks of structured PMMA layers, which are either realised wit ...

IEEE2004

Intercellular communication: role of gap junctions in establishing the pattern of ATP-elicited Ca2+ oscillations and Ca2+-dependent currents in freshly isolated aortic smooth muscle cells

Jean-Jacques Meister, Jean-Louis Bény

Cytosolic-free [Ca2+] was evaluated in freshly dissociated smooth muscle cells from mouse thoracic aorta by the ratio of Fura Red and Fluo 4 emitted fluorescence using confocal microscopy. The role of intercellular communication in forming and shaping ATP- ...

Elsevier2004

Fabrication of solid-state Nanopores for DNA analysis

Maïté Volatier

One of revolutionary technologies to sequence single molecules, such as DNA, is using nanopore devices. A single-channel with nanometer-scale aperture allows an extremely rapid electric analysis of such single molecules. The objective of this work is to fa ...

2004

Optimal feedback schemes over unknown channels

Emre Telatar

Communication over unknown discrete memoryless channels with instantaneous and perfect feedback is considered. For a given set of channels we define a notion of optimal coding schemes in terms of achievable rate and error exponent, and prove the existence ...

2004

Optimal feedback schemes over unknown channels

Emre Telatar, Aslan Tchamkerten

2004

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