Sensorineural hearing loss is the most common type of hearing loss worldwide, yet the underlying cause is typically unknown because the inner ear cannot be biopsied today without destroying hearing, and intracochlear cells have not been imaged with resolut ...
SPIE Society of Photo-optical Instrumentation Engineers2013
Aim: Treatment of sensorineural hearing loss could be advanced using novel drug carriers such as hyperbranched polylysine (HBPL) or lipid nanocapsules (LNCs). This study examined HBPL and LNCs for their cellular uptake and possible toxicity in vitro and in ...
Several dysmorphic syndromes affect the development of both the eye and the ear, but only a few are restricted to the eye and the external ear. We describe a developmental defect affecting the eye and the external ear in three members of a consanguineous f ...
A new hearing therapy based on direct acoustic cochlear stimulation was developed for the treatment of severe to profound mixed hearing loss. The device efficacy was validated in an initial clinical trial with four patients. This semi-implantable investiga ...
Institute of Electrical and Electronics Engineers2011
Open innovation has so far been studied mainly in high-tech, Multinational enterprises. This exploratory paper investigates if open innovation practices are also applied by small- and medium-sized enterprises (SMEs). Drawing oil I database collected from 6 ...
This paper presents a derivation and a physical interpretation of the equal area rule (EAR) for wire-grid simulation of surfaces. We propose a new procedure that leads to a formulation for obtaining the radii for an arbitrarily meshed surface. A simple com ...
