Advanced manufacturing | EPFL Graph Search

Advanced manufacturing is the use of innovative technology to improve products or processes, with the relevant technology being described as advanced, innovative or cutting edge. Advanced manufacturing industries increasingly integrate new innovative technologies in both products and processes. The rate of technology adoption and the ability to use that technology to remain competitive and add value to define the advanced manufacturing sector. World class manufacturing (WCM) integrates the latest-generation machinery with process/work systems to facilitate manufacturing based business development governed around manufactured products only, duly based over a high accent on product substitution or new product development. Advanced manufacturing centers upon improving the performance of US industry through the innovative application of technologies, processes and methods to product design and production. A survey done in 2010 by White House defined advanced manufacturing and stated

Nanovolcano microelectrode arrays: toward long-term on-demand registration of transmembrane action potentials by controlled electroporation

Arnaud Bertsch, Etienne de Coulon, Benoît Xavier Emmanuel Desbiolles, Nicolas Grégoire Maïno, Philippe Renaud, Stephan Rohr

Volcano-shaped microelectrodes (nanovolcanoes) functionalized with nanopatterned self-assembled monolayers have recently been demonstrated to report cardiomyocyte action potentials after gaining spontaneous intracellular access. These nanovolcanoes exhibit recording characteristics similar to those of state-of-the-art micro-nanoelectrode arrays that use electroporation as an insertion mechanism. In this study, we investigated whether the use of electroporation improves the performance of nanovolcano arrays in terms of action potential amplitudes, recording durations, and yield. Experiments with neonatal rat cardiomyocyte monolayers grown on nanovolcano arrays demonstrated that electroporation pulses with characteristics derived from analytical models increased the efficiency of nanovolcano recordings, as they enabled multiple on-demand registration of intracellular action potentials with amplitudes as high as 62 mV and parallel recordings in up to ~76% of the available channels. The performance of nanovolcanoes showed no dependence on the presence of functionalized nanopatterns, indicating that the tip geometry itself is instrumental for establishing a tight seal at the cell–electrode interface, which ultimately determines the quality of recordings. Importantly, the use of electroporation permitted the recording of attenuated cardiomyocyte action potentials during consecutive days at identical sites, indicating that nanovolcano recordings are nondestructive and permit long-term on-demand recordings from excitable cardiac tissues. Apart from demonstrating that less complex manufacturing processes can be used for next-generation nanovolcano arrays, the finding that the devices are suitable for performing on-demand recordings of electrical activity from multiple sites of excitable cardiac tissues over extended periods of time opens the possibility of using the devices not only in basic research but also in the context of comprehensive drug testing.

2020

Comparative study and selection criteria of linear motors

Samuel Chevailler

Initially, linear motors have been particularly dedicated to transportation systems. Nowadays, linear motors are meant to replace a system using a rotating motor and a transmission to realize a linear movement. With linear motors the performances increase considerably since the mechanical limitations are removed. This leads to a better precision, a higher acceleration and a higher speed of the moving part. Therefore, direct drives with linear motors are increasingly used in industrial applications although these solutions need often more investment costs. Different linear motor structures and technologies exist. They can be either induction or synchronous motors with a transverse or a longitudinal flux. Furthermore, linear motors may have several topologies. They can be either long or short stator and double or single sided. All these variants may be combined giving therefore numerous possibilities to perform a linear movement. Hence, to make the best choice for a given application, a global methodology based on the comparison of optimized motors is presented in the thesis. This design methodology is based on figure of merits which are bound to the specifications of the studied application. This method differs from a conventional one since optimized motors with the same objective function are compared. The optimized motors are obtained by an indirect method based on an optimization algorithm (Sequential Quadratic Programming, SQP). An indirect approach differs from the conventional deterministic one for which at least one parameter must be fixed to obtain a motor pre design, since there are constraints and validity domain which are introduced. The proposed methodology can be applied either to rotating or to linear motor design. The use of an optimization program to perform motor designs requires analytical motor models. The models developed in this thesis take into account the thermal behavior of the motors in order to achieve more realistic results. Furthermore, the analytical models of synchronous motors are thoroughly studied leading to several interesting conclusions. They are based on well known algorithms developed for rotating motors. The proposed models are very accurate in comparison with the FEM program, except for a transversal flux linear motor for which the obtained results are not worthwhile enough to be optimized. This is caused by the structure of the motor which is close to a reluctant motor and imposes to model the motor by a lumped magnetic scheme. Moreover, a global analysis of the windings due to the particularity of linear motor to have an even or odd number of poles is presented in the thesis. The methodology proposed in the thesis is successfully used for an innovative application which deals with a multi mobile system for a lift. For this lift, several cabins travel in the same shaft implying linear motors to move autonomously each cabin. First, by comparing the different motor technologies, the best motor type is selected. Afterwards, the motor windings for the selected motors are analyzed and compared in order to find the most adapted one for this application. The motor is finally optimized, leading to a motor design proposal. This motor design takes into account the thermal behavior, the material cost and the electrical characteristic of the linear motor.

EPFL2006