Publications associées à Fusion gene

Cholesterol-Containing Liposomes Decorated With Au Nanoparticles as Minimal Tunable Fusion Machinery

Francesco Stellacci, Paulo Henrique Jacob Silva, Ester Canepa, Giulia Rossi

Membrane fusion is essential for the basal functionality of eukaryotic cells. In physiological conditions, fusion events are regulated by a wide range of specialized proteins, operating with finely tuned local lipid composition and ionic environment. Fusog ...

WILEY-V C H VERLAG GMBH2023

Screening for drivers of SARS-CoV-2 uptake

Christoph Merten, Alexis Louis Autour

Genetic and cellular drivers of the cellular uptake of SARS-CoV-2 can be screened at high throughput via droplet microfluidics and size-exclusion methods for the analysis of the formation of fusions between cells expressing the virus's spike protein and ce ...

Nature Portfolio2023

Measuring reporter activity domain in EPI aggregates and Gastruloids.ijm

Matthias Lütolf, Olivier Burri, Romain Guiet, Mehmet Ugur Girgin

This imagej macro analyses the reporter intensity activity and expression domain in EPI aggregates and Gastruloids. ...

Zenodo2022

EUROfusion-theory and advanced simulation coordination (E-TASC): programme and the role of high performance computing

Laurent Villard, Jonathan Graves, Eric Serre

This paper is a written summary of an overview oral presentation given at the 1st Spanish Fusion High Performance Computer (HPC) Workshop that took place on the 27 November 2020 as an online event. Given that over the next few years ITER24 will move to its ...

2022

Tracking blobs in the turbulent edge plasma of a tokamak fusion device

Christian Gabriel Theiler, Nicola Offeddu, Woonghee Han

The analysis of turbulence in plasmas is fundamental in fusion research. Despite extensive progress in theoretical modeling in the past 15 years, we still lack a complete and consistent understanding of turbulence in magnetic confinement devices, such as t ...

Nature Portfolio2022

Analysis and modelling of momentum transport based on NBI modulation experiments at ASDEX Upgrade

Basil Duval, Emiliano Fable, Giovanni Tardini

The prediction of plasma rotation is of high interest for fusion research due to the effects of the rotation upon magnetohydrodynamic (MHD) instabilities, impurities, and turbulent transport in general. In this work, an analysis method was studied and vali ...

2022

SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres

Joachim Lingner, Wareed Ahmed, Verena Pfeiffer, Marianna Feretzaki, Aleksandra Vancevska

Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) has been implicated in X-chromosome inactivation, imprinting, and DNA damage repair, and mutations in SMCHD1 can cause facioscapulohumeral muscular dystrophy. More re ...

WILEY2020

γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia

Jörg Hülsken, Oliver Hantschel, Anja Irmisch

The BCR-ABL1 fusion protein is the cause of chronic myeloid leukemia (CML) and of a significant fraction of adult-onset B cell acute lymphoblastic leukemia (B-ALL) cases. Using mouse models and patient-derived samples, we identified an essential role for γ ...

2019

Bioluminescent Antibodies for Point-of-Care Diagnostics

Kai Johnsson, Rudolf Griss, Alberto Schena, Qiuliyang Yu, Lin Xue

We introduce a general method to transform antibodies into ratiometric, bioluminescent sensor proteins for the no-wash quantification of analytes. Our approach is based on the genetic fusion of antibody fragments to NanoLuc luciferase and SNAP-tag, the lat ...

Wiley-VCH Verlag GmbH2017

The gene family-free median of three

Metin Balaban

Background: The gene family-free framework for comparative genomics aims at providing methods for gene order analysis that do not require prior gene family assignment, but work directly on a sequence similarity graph. We study two problems related to the b ...

2017