Publications associées (65)

Micrometer-resolution X-ray tomographic full-volume reconstruction of an intact post-mortem juvenile rat lung

Goran Lovric, Marco Stampanoni, Anders Larsson

In this article, we present an X-ray tomographic imaging method that is well suited for pulmonary disease studies in animal models to resolve the full pathway from gas intake to gas exchange. Current state-of-the-art synchrotron-based tomographic phase-con ...
SPRINGER2020

SLC25A51 is a mammalian mitochondrial NAD(+) transporter

Kai Johnsson, Liang Wang

Mitochondria require nicotinamide adenine dinucleotide (NAD(+)) to carry out the fundamental processes that fuel respiration and mediate cellular energy transduction. Mitochondrial NAD(+) transporters have been identified in yeast and plants(1,2), but thei ...
NATURE RESEARCH2020

Adaptive Compliant Foot Design for Salamander Robots

Auke Ijspeert, Kamilo Andres Melo Becerra, Robin Thandiackal, Laura Isabel Paez Coy

Aquatic stepping gaits in animals arguably display higher speed performance as well as energetic efficiency compared to other gaits using the limbs (i.e walking). This suggest that the foot structure and function contributes at a great extent on the propul ...
IEEE2019

Understanding the Mechanobiology of Early Mammalian Development through Bioengineered Models

Matthias Lütolf, Stefano Davide Vianello

Research in developmental biology has been recently enriched by a multitude of in vitro models recapitulating key milestones of mammalian embryogenesis. These models obviate the challenge posed by the inaccessibility of implanted embryos, multiply experime ...
2019

Nuclear RNR-alpha antagonizes cell proliferation by directly inhibiting ZRANB3

Yimon Aye, Yuan Fu

Since the origins of DNA-based life, the enzyme ribonucleotide reductase (RNR) has spurred proliferation because of its rate-limiting role in de novo deoxynucleoside-triphosphate (dNTP) biosynthesis. Paradoxically, the large subunit, RNR-alpha, of this obl ...
2018

Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development

Denis Duboule, Marion Leleu, Pierre Raymond Fabre

Background: Global analyses of gene expression during development reveal specific transcription patterns associated with the emergence of various cell types, tissues, and organs. These heterogeneous patterns are instrumental to ensure the proper formation ...
BMC2018

Compliant universal grippers as adaptive feet in legged robots

Auke Ijspeert, Mehmet Hasan Mutlu, Simon Lukas Hauser

This work investigates the usage of compliant universal grippers as a novel foot design for legged locomotion. The method of jamming of granular media in the universal grippers is characterized by having two distinct states: a soft, fluid-like state which ...
2018

Detecting animals in African Savanna with UAVs and the crowds

Stéphane Joost, Devis Tuia

Unmanned aerial vehicles (UAVs) offer new opportunities for wildlife monitoring, with several advantages over traditional field-based methods. They have readily been used to count birds, marine mammals and large herbivores in different environments, tasks ...
Elsevier2017

Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock

Denis Duboule

Collinear regulation of Hox genes in space and time has been an outstanding question ever since the initial work of Ed Lewis in 1978. Here we discuss recent advances in our understanding of this phenomenon in relation to novel concepts associated with larg ...
Cold Spring Harbor Laboratory Press2017

A multidirectional gravity-assist algorithm that enhances locomotor control in patients with stroke or spinal cord injury

Auke Ijspeert, Grégoire Courtine, Jocelyne Bloch, Joachim von Zitzewitz, Nicolas Francis Fumeaux, Marco Capogrosso, Rubia van den Brand, Jean-Baptiste Mignardot, Selin Anil, Jessica Lanini

Gait recovery after neurological disorders requires remastering the interplay between body mechanics and gravitational forces. Despite the importance of gravity-dependent gait interactions and active participation for promoting this learning, these essenti ...
Amer Assoc Advancement Science2017

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