Concept

Hyponatrémie

Publications associées (33)

Neuroprotective role of lactate after cerebral ischemia

Rolf Gruetter, Pierre Magistretti, Hongxia Lei, Jonathan Thevenet

It is well established that lactate can be used as an energy substrate by the brain by conversion to pyruvate and a subsequent oxidation in the mitochondria. Knowing the need for readily metabolizable substrates directly after ischemia and the protective e ...

2009

Calcium dynamics and vasomotion in arteries subject to isometric, isobaric, and isotonic conditions

Jean-Jacques Meister, Roger Sauser, Jean-Louis Bény, Michèle Koenigsberger, Dominique Seppey

In vitro, different techniques are used to study the smooth muscle cells' calcium dynamics and contraction/relaxation mechanisms on arteries. Most experimental studies use either an isometric or an isobaric setup. However, in vivo, a blood vessel is neithe ...

2008

Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease

The neuropathological and clinical symptoms of Huntington's disease (HD) can be simulated in animal model with systemic administration of 3-nitropropionic acid (3-NP). Energy defects in HD could be ameliorated by administration of coenzyme Q10 (CoQ10), cre ...

2006

Single potential electrophoresis on-chip using Pressure Pulse Injection

Martinus Gijs, Frédéric Lacharme

We propose two new injection techniques for use in electrophoresis microchips, which we call 舖Front Gate Pressure Injection舗 and 舖Back Gate Pressure Injection舗. Both techniques enable a controlled and variable size sample introduction with reduced bias com ...

2005

Control of yeast fed-batch process through regulation of extracellular ethanol concentration

Urs von Stockar, Sergio Valentinotti, Christopher Cannizzaro

At high growth rates, the biomass yield of baker's yeast (Saccharomyces cerevisiae) decreases due to the prodn. of ethanol. For this reason, it is std. industrial practice to use a fed-batch process whereby the specific growth rate, m, is fixed at a level ...

Springer-Verlag2004

Nuglets: a Virtual Currency to Stimulate Cooperation in Self-Organized Mobile Ad Hoc Networks

Jean-Pierre Hubaux, Levente Buttyan

In mobile ad hoc networks, it is usually assumed that all the nodes belong to the same authority; therefore, they are expected to cooperate in order to support the basic functions of the network such as routing. In this paper, we consider the case in which ...

2001

Differential effect of thyroid hormone deficiency on the growth of calretinin-expressing neurons in rat spinal cord and dorsal root ganglia

Pierre Magistretti, Thibault Adrien Kuntzer

The development of spinal cord or dorsal root ganglia neurons expressing calretinin (CR) was studied in thyroid hormone-deficient rats. Immunocytochemical and morphometric analyses showed that the hypothyroidism induced a significant decrease in the number ...

2000

Salt restriction induces pseudohypoaldosteronism type 1 in mice expressing low levels of the beta-subunit of the amiloride-sensitive epithelial sodium channel

Qian Wang, Friedrich Beermann

The amiloride-sensitive epithelial sodium channel (ENaC) is a heteromultimer of three homologous subunits (alpha-, beta-, and gamma- subunits). To study the role of the beta-subunit in vivo, we analyzed mice in which the betaENaC gene locus was disrupted. ...

1999

A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism

Qian Wang, Friedrich Beermann

Aldosterone-dependent epithelial sodium transport in the distal nephron is mediated by the absorption of sodium through the highly selective, amiloride-sensitive epithelial sodium channel (ENaC) made of three homologous subunits (alpha, beta, and gamma). I ...

1997

Stimulation by nicotine of enteric inhibitory nerves and release of vasoactive intestinal peptide in the taenia of the guinea-pig caecum

Pierre Magistretti, Jean-Luc Martin

The stimulation by nicotine of intramural nerves and the role of ATP and vasoactive intestinal peptide (VIP) as inhibitory transmitters were studied in the isolated taenia of the guinea-pig caecum. Nicotine (4-32 microM) caused transient, concentration-dep ...

1988

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