Concept

Syndrome respiratoire aigu sévère

Publications associées (48)

Wastewater-based estimation of the effective reproductive number of SARS-CoV-2

Tamar Kohn, Krista Rule Wigginton, Xavier Fernandez Cassi, Timothy R. Julian

Background The effective reproductive number, Re, is a critical indicator to monitor disease dynamics, inform regional and national policies, and estimate the effectiveness of interventions. It describes the average number of new infections caused by a sin ...

2021

Identification of Vaccine Effects When Exposure Status Is Unknown

Mats Julius Stensrud

Results from randomized controlled trials (RCTs) help determine vaccination strategies and related public health policies. However, defining and identifying estimands that can guide policies in infectious disease settings is difficult, even in an RCT. The ...

2021

Assessing the impact of non-pharmaceutical interventions on SARS-CoV-2 transmission in Switzerland

Following the rapid dissemination of COVID-19 cases in Switzerland, large-scale non-pharmaceutical interventions (NPIs) were implemented by the cantons and the federal government between 28 February and 20 March 2020. Estimates of the impact of these inter ...

E M H SWISS MEDICAL PUBLISHERS LTD2020

Analysis of DP3T - Between Scylla and Charybdis

Serge Vaudenay

To help fighting the COVID-19 pandemic, the Pan-European Privacy-Preserving Proximity Tracing (PEPP-PT) project proposed a Decentralized Privacy-Preserving Proximity Tracing (DP3T) system. This helps tracking the spread of SARS-CoV-2 virus while keeping th ...

2020

Reusability of filtering facepiece respirators after decontamination through drying and germicidal UV irradiation

Véronique Michaud, David Vernez, Guillaume Suarez, Kiattisak Batsungnoen

Introduction During pandemics, such as the SARS-CoV-2, filtering facepiece respirators plays an essential role in protecting healthcare personnel. The recycling of respirators is possible in case of critical shortage, but it raises the question of the effe ...

2020

Structural investigation of ACE2 dependent disassembly of the trimeric SARS-CoV-2 Spike glycoprotein

Henning Paul-Julius Stahlberg, David Hacker, Florence Pojer, Dongchun Ni, Kelvin Ka Ching Lau

The human membrane protein Angiotensin-converting enzyme 2 (hACE2) acts as the main receptor for host cells invasion of the new coronavirus SARS-CoV-2. The viral surface glycoprotein Spike binds to hACE2, which triggers virus entry into cells. As of today, ...

2020

AltitudeOmics: Spontaneous Baroreflex Sensitivity During Acclimatization to 5,260 m: A Comparison of Methods

Jean-Marc Vesin, Sasan Yazdani

Introduction Baroreflex sensitivity (BRS) is essential to ensure rapid adjustment to variations in blood pressure (BP). Spontaneous baroreflex function can be assessed using continuous recordings of blood pressure. The goal of this study was to compare fou ...

FRONTIERS MEDIA SA2019

Severe viral respiratory infections in children with IFIH1 loss-of-function mutations

Jacques Fellay, Amalio Telenti, Istvan Bartha, Christian Hammer, Thomas Junier, Samira Asgari

Viral respiratory infections are usually mild and self-limiting; still they exceptionally result in life-threatening infections in previously healthy children. To investigate a potential genetic cause, we recruited 120 previously healthy children requiring ...

Natl Acad Sciences2017

Whole cell screen based identification of spiropiperidines with potent antitubercular properties

Stewart Cole, Ruben Hartkoorn

Whole cell based screens to identify hits against Mycobacterium tuberculosis (Mtb), carried out under replicating and non-replicating (NRP) conditions, resulted in the identification of multiple, novel but structurally related spiropiperidines with potent ...

Elsevier2015

Estimating the real-time respiratory rate from the ECG with a bank of notch filters

Jean-Marc Vesin, Leila Mirmohamadsadeghi

The respiratory rate is an important vital sign that needs to be monitored continuously in clinical and non-clinical health monitoring applications. It is commonly estimated from electrocardiogram (ECG)-derived respiratory waveforms such as the respiratory ...

2015

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