Concept

Endobrachyœsophage

Publications associées (10)

Bile Acids Increase Levels of MicroRNAs 221 and 222, Leading to Degradation of CDX2 During Esophageal Carcinogenesis

BACKGROUND & AIMS: Bile reflux contributes to development of Barrett's esophagus (BE) and could be involved in its progression to esophageal adenocarcinoma (EAC). We investigated whether bile acids affect levels or functions of microRNAs (MIRs) 221 and 222 ...

Elsevier2013

Defining new criteria for selection of cell-based intestinal models using publicly available databases

Michel Aguet, Mauro Delorenzi, Pascale Anderle Pedone, Thierry Sengstag

Background: The criteria for choosing relevant cell lines among a vast panel of available intestinal-derived lines exhibiting a wide range of functional properties are still ill-defined. The objective of this study was, therefore, to establish objective cr ...

BioMed Central2012

From gut homeostasis to cancer

Freddy Radtke

The mammalian intestine has one of the highest turnover rates in the body. The intestinal epithelium is completely renewed in less than a week. It is divided into spatially distinct compartments in the form of finger-like projections and invaginations that ...

2006

In vivo autofluorescence imaging of early cancers in the human tracheobronchial tree with a spectrally optimized system

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger

The changes in the autofluorescence characteristics of the bronchial tissue is of crucial interest as a cancer diagnostic tool. Evidence exists that this native fluorescence or autofluorescence of bronchial tissues changes when they turn dysplastic and to ...

2003

Optimization of the spectral design used to detect early carcinoma in the human tracheo-bronchial tree by autofluorescence imaging

Hubert van den Bergh, Georges Wagnières, Tanja Gabrecht

The early detection and localization of bronchial cancer remains a challenging task. Autofluorescence bronchoscopy is emerging as a useful diagnostic tool with improved sensitivity and specificity. Evidence exists that the native fluorescence or autofluore ...

2003

Detection of early bronchial carcinoma by imaging of the tissue autofluorescence

Hubert van den Bergh, Georges Wagnières, Matthieu Philippe Emmanuel Zellweger, Tanja Gabrecht

Early detection and localisation of bronchial cancer remains a challenging task. One approach is to exploit the changes in the autofluorescence characteristics of the bronchial tissue as a diagnostic tool with improved sensitivity. Evidence exists that thi ...

2001

Photodynamic therapy for 101 early cancers of the upper aerodigestive tract, the esophagus, and the bronchi: a single-institution experience

Hubert van den Bergh, Georges Wagnières, Alain Woodtli

Cancer, when detected at an early stage, has a very good probability of being eradicated by surgery or radiotherapy. However, less aggressive treatments also tend to provide high rates of cure without the side effects of radical therapy. We report on the r ...

Hindawi Publishing Corporation1999

Clinical assessment of fluorescence cystoscopy during transurethral bladder resection in superficial bladder cancer

Hubert van den Bergh, Georges Wagnières

The prognosis of superficial bladder cancer in terms of recurrence and disease progression is related to bladder tumor multiplicity and the presence of concomitant "plane" tumors such as high-grade dysplasia and carcinoma in situ. This study in 33 patients ...

1997

Optimizing light dosimetry in photodynamic therapy of early stage carcinomas of the esophagus using fluorescence spectroscopy

Hubert van den Bergh

BACKGROUND AND OBJECTIVE: Under standardized conditions (drug and light dose, timing), the result of the photodynamic therapy (PDT) of carcinomas of the esophagus with tetra(meta-hydroxyphenyl)chlorin (mTHPC) shows large variations between patients. STUDY ...

1996

Photofrin II pharmacokinetics and optical dosing in tissue: apparatus and clinical measurements for the pharynx, esophagus, and tracheobronchial tree

Hubert van den Bergh, Georges Wagnières, André Châtelain

The timing has been optimized of photodetection (and possibly also phototherapy) of early cancer in the upper aerodigestive tract and bronchi and the relative concn. of fluorescent components of Photofrin II measured in patients as a function of the time a ...

1991

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