Publications associées (6)

Impact of HSD11B1 polymorphisms on BMI and components of the metabolic syndrome in patients receiving psychotropic treatments

Pierre Magistretti, Murielle Bochud, Aurélie Delacrétaz

Background Metabolic syndrome (MetS) associated with psychiatric disorders and psychotropic treatments represents a major health issue. 11 beta-Hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) is an enzyme that catalyzes tissue regeneration of active cor ...
Lippincott Williams & Wilkins2015

A role for brain glucocorticoid receptors in contextual fear conditioning: dependence upon training intensity

Maria del Carmen Sandi Perez, Maria Isabel Cordero Campana

We studied the possible involvement of corticosteroids in the establishment and long-term expression of contextual fear conditioning and questioned whether a corticosteroid action might be dependent upon stimulus intensity at training. Experiments included ...
1998

Piracetam facilitates long-term memory for a passive avoidance task in chicks through a mechanism that requires a brain corticosteroid action

Maria del Carmen Sandi Perez

We investigated the effects of piracetam, a nootropic, on learning and memory formation for a passive avoidance task in day-old chicks. To test for the possible cognitive-enhancing properties of piracetam, a weak learning version of this task--whereby chic ...
1998

Nitric oxide synthesis inhibitors prevent rapid behavioral effects of corticosterone in rats

Maria del Carmen Sandi Perez

Corticosteroid actions at the brain can modulate neural function and behavioral processes. Classic corticosteroid effects are mediated through intracellular receptors which act primarily by regulation of DNA transcription. However, an alternative nongenomi ...
1996

Corticosterone facilitates long-term memory formation via enhanced glycoprotein synthesis

Maria del Carmen Sandi Perez

Long-term memory formation for a passive avoidance task in one-day-old chicks requires a late phase of synaptic glycoprotein synthesis (including the neural cell adhesion molecule), commencing 5.5 h post-training. This phase occurred in chicks trained with ...
1995

Corticosteroid receptor antagonists are amnestic for passive avoidance learning in day-old chicks

Maria del Carmen Sandi Perez

Glucocorticoids can modulate behavioural processes and neural plasticity. They are released during learning situations and can trigger neural actions through binding to brain receptors. We hypothesized that a glucocorticoid action could play a critical rol ...
1994

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