Concept
Bioluminescence
Personnes associées (18)
Georges Wagnières
Georges Wagnières a obtenu son diplôme (MSc) en physique à l'Université de Lausanne, Suisse, en 1986. Il a reçu son doctorat ès science (PhD) en physique (Optique Biomédicale) de l'Ecole Polytechnique Fédérale de Lausanne (EPFL) en 1992, et a effectué un travail de postdoctorat dans les "Wellman Laboratories of Photomedicine" (Harvard Medical School) situés à Boston, MA, USA, en 1993 et 1994. Il a aussi obtenu, en 2001, un "Master in management of technology" délivré par l'Ecole des Hautes Etudes Commerciales (HEC) de l'Université de Lausanne et l'EPFL. Depuis 1994, il gère un groupe de recherche de l'EPFL actif dans les domaines suivants: - Caractérisation et détection de lésions cancéreuses par spectroscopie et imagerie de fluorescence ainsi que par imagerie à fort grossissement. - Traitement du cancer ainsi que d'autres pathologies associées à des désordres immunologiques (maladie de Crohn, Colite ulcéreuse) ou vasculaires par thérapie photodynamique (PDT). - Développement préclinique et clinique de photosensibilisateurs, de marqueurs fluorescents et d'instruments optiques pour le photodiagnostic. - Traitement de diverses pathologies, y compris les maladies neuro-dégénératives (Parkinson, Alzheimer), par photobiomodulation. - Monitorage de la dose optique pour la PDT basée sur l'imagerie de fluorescence de photosensibilisateurs. - Induction de l'extravasation d'agent chimiothérapeutiques par PDT. - Mesure in vivo de la concentration d'oxygène dans des tissus biologiques par spectroscopie et imagerie optiques résolues en temps. - Monitorage d'un traitement au laser de la rétine par imagerie de reflectance. - Développement de distributeurs de lumière pour des applications biomédicales. - Dosimétrie de lumière / Radiométrie. - Spectroscopie et imagerie en optique biomédicale. Georges Wagnières est aussi co-fondateur et a présidé une société "spin-off" de l'EPFL: - Medlight SA, fondée en 1997, qui développe, produit et commercialise des distributeurs de lumière pour la thérapie photodynamique. Georges Wagnières est l'auteur et co-auteur de plus de 235 articles scientifiques dont 150 ont été publiés dans des revues internationales ayant un comité de relecture (review board). De plus, il est inventeur de 18 brevets. Finalement, il supervise ou a supervisé 12 doctorants et enseigne actuellement à l'EPFL l'optique biomédicale et la photomédecine au niveaux "master". Ces cours sont aussi donnés à l'Ecole doctorale (EDCH, EDSV) de l'EPFL. Finalement, il donne le cours intitulé "Physique Générale I" aux biologistes de première année inscrits à l'Ecole de Biologie de l'Université de Lausanne. PUBLICATIONS PRINCIPALES: SVP visiter: https://www.epfl.ch/labs/lifmet/wagnieres/publications/
Jean-Claude Bünzli
Jean-Claude Bünzli was born in 1944. He earned a degree in chemical engineering in 1968 and a PhD in 1971 (Swiss Federal Institute of Technology, Lausanne) for his work on the kinetic behaviour of Nb and Ta pentachloride adducts. He spent two years at the University of British Columbia as a teaching postdoctoral fellow (photoelectron spectroscopy) and one year at the Swiss Federal Institute of Technology in Zürich (physical organic chemistry).
Positions
He was appointed assistant-professor at the University of Lausanne in 1974 and started a research program on the spectrochemical properties of f-elements. He was promoted as a full professor of inorganic and analytical chemistry in 1980. He transferred to EPFL in 2001 where he directed the Laboratory of Lanthanide Supramolecular Chemistry until 2010.
From 2009 to 2013, he was World Class University Professor at Korea University (South Korea) helping developing a new research center for photovoltaics. In 20154-2015 he acted as visiting professor at FJIRSM (Fuzhou, Fujian), a laboratory of the Chinese Academy of Sciences.
He presently holds the Dr Kennedy Wong Distinguished Visiting Professorship at Hong Kong Baptist University (3 months/year) and a position as Distinguished Scholar at University of Technology, Sydney (NSW, Australia, 1 month/year).
Administrative and reviewer duties
He acted as the elected Dean of the Faculty of Sciences (1990-1991) and as one of the elected Vice-Rectors of the University (1991-1995), in charge of students' affairs and of research programs in the field of biomedical sciences. He held a position of invited professor at the Université Louis Pasteur, Strasbourg in 1996 and at the Science University of Tokyo in 1998. In 1989, he founded the European Rare Earths and Actinide Society which coordinate international conferences in the field (cf. http://ereswww.epfl.ch).
He served as a World Bank Project Specialist within the framework of the Chinese Provincial Universities Development Project (Northwest China, 1989) and as a member of a Panel in charge of evaluating chemical research at Norwegian universities (1997). In 2001, he was hired as "Peer leader" for the evaluation of the Swiss universities of applied sciences. In 2005, he acted as a member of the "Physical Inorganic Panel" of the Science Foundation of Ireland and in 2006 he was nominated to the "Chemistry Panel" of the same foundation.
He is a member of the Editorial Board of Spectroscopy Letters, associate editor-in-chief of the Journal of Rare Earths, and senior editor of the Handbook on the Physics and Chemistry of Rare Earths (54 volumes published to date).
Teaching
Regarding teaching, he has directed the joint project of the universities of Geneva, Lausanne, Neuchâtel and Fribourg "General chemistry for students enrolled in a life sciences curriculum", within the frame of the "Swiss virtual campus", a program sponsored by the Conference of Swiss universities and the Swiss federal office for science and education (2000-2004). Web site: http://chimge@epfl.ch
Research
His research is centered on lanthanide luminescent molecular and supramolecular edifices, with main applications in biology & medicine. He is the author or the co-author of 350 research papers, 260 contributed communications and has presented 285 invited conferences, seminars, and courses. He has collected >22800 citations (h-index 72).
Anne-Sophie Chauvin
Web of Science Researcher ID F-4905-2011
Google Scholar page: https://scholar.google.ch/citations?user=O_HhJUEAAAAJ&hl=fr&oi=ao
ORCID number is 0000-0001-9222-3866
Anne-Sophie Chauvin studied chemistry and biology at the university Paris V-René Descartes in France where she did a PhD in organic chemistry, working on mimetic complexes of the active site of Nitrile Hydratase, under the supervision of Prof. Jean-Claude Chottard. On 1999 she moved for 20 months to the University of Geneva, for a post-doctoral stay under the supervision of Prof. Alexandre Alexakis, where she focused on the determination of the absolute configuration of chiral alcohols using Organophosphorous Diamine Derivatizing Agents by 31P and 1H NMR Spectroscopy. On 2000 she joined the group of Prof Jean-Claude G. Bünzli and was appointed part-time lecturer in 2001, assuming teaching and research responsibilities. On 2006, she obtained the habilitation to direct research from the University René Descartes (HDR, Paris V, France) and since october 2007 she is Maître d'Enseignement et de Recherche at the EPFL. In 2010, she joigned the Laboratory for Photonics and Interfaces (LPI), headed by Pr. Michaël Graëtzel. Since the end of 2014, with the arrival of Dr Marinella Mazzanti at EPFL, she is back to lanthanide chemistry, dealing with coordination polymers.
Her research interests concern supramolecular chemistry with the design of ligands which form water soluble complexes with luminescent lanthanides in view of biological applications. She is also interested in the synthesis of ligands and polymers for the extraction of lanthanide ions with high selectivity, and in the development of invisibke inks. She also developed organic dyes for dyes sensitized solar cells DSSC. She is now focusing on coordination polymers with luminescent properties and catalytic activity.
Anne-Sophie Chauvin is involved in the teaching of General and Analytical Chemistry for students enrolled on first year in Pharmacy and Biology (UNIL): ex-cathedra courses (Chimie Générale et analytique I et II, approfondissement en chimie analytique pour pharmaciens) and exercices.
She is in charge of practical sessions for students enroled in chemistry, forensic sciences, pharmacy and biology.
She is elected at the FSB Faculty Council and was member of the EPFL Assembly (AE) for 6 years, until 2018.
She was member of the Management committee of the Cost CM 1006 action entitled Eufen: European F-Element Network.
She is Member of the Swiss Chemical Society (SCS) and Fellow of the Royal Society of Chemistry (FRSC).
Giorgio Margaritondo
De nationalité américaine et suisse, Giorgio Margaritondo est né à Rome (Italie) en 1946. Il a reçu la Laurea cum laude en physique de l'Université de Rome en 1969. De 1969 à 1978, il a travaillé pour le Consiglio Nazionale delle Ricerche (CNR), à Rome, à Frascati et, pendant la période 1975-1977, chez Bell Laboratories aux Etats-Unis. De 1978 à 1990, il est professeur de physique à l'Université du Wisconsin, à Madison (Etats-Unis); en 1984, il est nommé vice-directeur au Centre de rayonnement synchrotron de la même université. En 1990, il est engagé à l'EPFL comme professeur ordinaire et dirige l'Institut de physique appliquée au Département de physique. Il a été également membre honoraire du corps professoral de l'Université Vanderbilt à Nashville. En 2001 il a été nommé doyen de la Faculté des sciences de base de l'EPFL; en 2004, il a été nommé Vice-président pour les affaires académiques.; en 2010 et jusqu'à sa retraite de l'EPFL en 2016 il est devenu Doyen de la formation continue. A côté de ses cours de physique générale, son activité de recherche porte sur la physique des semiconducteurs et des supraconducteurs (états électroniques, surfaces, interfaces) et des systèmes biologiques; ses principales méthodes expérimentales sont la spectroscopie et la spectromicroscopie électroniques, l'imagerie aux rayons x et la microscopie SNOM, y compris les expériences avec le rayonnement synchrotron et le laser à électrons libres. Auteur d'environ 700 articles scientifiques et de 9 livres, il a aussi été responsable de 1995 à 1998 des programmes scientifiques du Synchrotron ELETTRA à Trieste. Depuis 1997, il a été le coordinateur de la table ronde de la Commission européenne pour le rayonnement synchrotron, et président du conseil de la "Integrated Initiative" de la Commission européenne pour les synchrotrons et les lasers à électrons libres (IA-SFS, ensuite ELISA), le plus grand réseau au monde de laboratoires dans ce domaine. En 2011-2015, il a été Editor-in-Chief du Journal of Physics D (Applied Physics). A présent, il est vice-président du conseil de l'Università della Svizzera Italiana (USI) et président du Scientific and Technological Committee de l'Istituto Italiano di Tecnologia (IIT). Il est "Fellow" de l'American Physical Society et de l'American Vacuum Society; il est également "Fellow and Chartered Physicist" de l'Institute of Physics.
Anders Meibom
Anders Meibom obtained his PhD in physics from the University of Southern Denmark in 1997. This was followed by two and a half years of PostDoc work at the Hawaii Institute for Geophysics and Planetology, where he conducted mineralogical studies of primitive chondritic meteorites. From 2000 to 2005, he was Research Associate in the Geological & Environmental Sciences, Stanford University, where he represented Stanford in the USGS-Stanford ion microprobe laboratory. In 2005, he became proifessor at the Muséum National dHistoire Naturelle in Paris. From 2006 to 2011 he was the director of the French national NanoSIMS laboratory. Since January 2012, he is professor at the EPFL in the School of Architecture, Civil and Environmental Engineering (ENAC). From April 2014, he is professor ad personam at the Institute of Earth Sciences, University of Lausanne.