Concept
Bêta-oxydation
Personnes associées (36)
Johan Auwerx
Johan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Rolf Gruetter
Awards:
1999 Young Investigator Award Plenary Lectureship
, International Society for Neurochemistry
2011 Fellow
, ESMRMB
2011 Teaching Award
, Section Sciences de la Vie, EPFL
Urs von Gunten
URS VON GUNTEN
born in Baden (Switzerland) on 20/10/1959
RESEARCH INTERESTS
Drinking water quality and water treatment. Unit processes and process combinations (adsorption processes, membrane processes, oxidation processes). Chemical oxidation and advanced oxidation processes: kinetics and mechanisms of formation of disinfection by-products and degradation of micropollutants. Assessment of toxicology of of transformation products. Biogeochemical processes in riverbank filtration systems. In situ and out-of-ground treatment of groundwaters
EDUCATION
Diploma Swiss Federal Institute of Technology (ETH) Zürich, Department of Chemistry,Switzerland, 1983
Ph.D.Swiss Federal Institute of Technology (ETH) Zürich, Switzerland, 1989.
AWARDS AND FELLOWSHIPS
2018 Clarivate Analytics Highly Cited Researcher
2015 Thomson Reuters Highly Cited Researcher
2015 Recipient of the Harvey Rosen Award 2015 of the International Ozone Association
2015 Professorship under the Chinese Academy of Sciences President’s International Fellowship Initiative for Distinguished Scientists
2014 Thomson Reuters Highly Cited Researcher
2013 Distinguished Lecturer for AEESP at the American Water Works Association Annual Conference, Denver, June 10, 2013
2012-to date Adjunct Professor at the Gwangju Institute of Science and Technology, Korea
2011 Full Professor at the Swiss Federal Institute of Technology, Lausanne (EPFL)
2010 Adjunct Professor at the State Key Laboratory of Environmental Aquatic
Chemistry, Chinese Academy of Sciences
2010 Adjunct Professor at the Curtin University of Technology, Perth,
Australia
2007 Honorary Professorship at the Harbin Institute of Technology, Harbin,
China
2007 Recipient of the Harvey Rosen Award 2007 of the International Ozone
Association
2007 Environmental Science and Technology Excellence in Review Award
2006 Professor title at ETHZ, Department of Environmental Sciences
2001 Recipient of the Harvey Rosen Award 2001 of the International Ozone
Association
1999 Recipient of the Marteen Schalekamp Award 1999 of the IWSA
1993 Recipient of a short-term fellowship of the Swiss National Science
Foundation in 1993 and 1994
1993 EERO short-term fellowship-holder
PROFESSIONAL RECORD
2013-2016 Head of transdisciplinary project “Regional Water Supply Basel Country 21”, Eawag
2010-2017 Head of Competence Center for Drinking Water, Eawag
2008/2009 Visiting Professor at the Curtin Water Quality Research Centre,
Curtin University of Technology, Perth, Australia
2004-to date Deputy head of department Water Resources and Drinking Water,
Eawag
2004-2008 Head of the cross-cutting project Drinking water for the 21st
century, Eawag
2000 2004 Head of department Water Resources and Drinking Water, Eawag
2000/2001 Sabbatical at University of Colorado, Boulder
1998 - 1999 Head of department of Chemistry, Eawag
1995 - 2011 Lecturer at Swiss Federal Institute of Technology (ETH) Zürich,
Switzerland.
1995- to date Group leader of the drinking water group of the chemistry
department at Eawag
1994/93 Visiting Scientist at the International Research Center for
Water and Environment of Lyonnaise des Eaux (8 months),
CIRSEE, Le Pecq, France
since 1992 Research Scientist at Eawag
1989 - 1991 Postdoctoral Researcher at Eawag
1984 - 1989 Research Assistant, Swiss Federal Institute of Technology,
Zürich
EDITORIAL ACTIVITIES
Associate Editor Environmental Science and Technology (2010/2011)
Guest Editor Water Research for special issue on Emerging
Contaminants (2010)
Guest Editor Journal of water supply: Research and
Technology-Aqua for a special issue on Oxidation Processes (2008)
Member of the editorial board of the journal Ozone: Science and Engineering.
Member of the editorial board of Journal of water supply: Research and Technology-Aqua.
FORMER PROFESSIONAL ACTIVITIES
2016 Co-organizer of PEAK seminar ”Neue Herausforderungen und Lösungsansätze in der Wasserversorgung – Fallbeispiele aus dem Kanton BL”. Dübendorf, November 11, 2016
2015 Organizer of PEAK seminar “Micropollutants in drinking water”, Dübendorf, October 30
2014 Co-organizer of the Eawag Infotag “Wasserversorgung und Uferfiltration – ein System unter Druck?” Dübendorf, September 9, 2014
2014 Co-organizer of a Symposium “Advanced oxidation processes for water treatment” 5th EuCheMS Chemistry Congress 2014, Aug. 31 – Sept. 4, Istanbul, Turkey, 2014
2013 Co-Organizer of PEAK seminar on “Oxidation and Disinfection Processes”, Aug. 30, Dübendorf
2013 Co-Organizer of the Micropoll & Ecohazard Conference, Zürich, June 17-19, 2013
2013 Co-Organizer of the session “Advanced Oxidation – Technologies and Applications, Leading Edge Technology (LET) Conference, Bordeaux, June 2-6, 2013
2011 Co-Organizer of Korean-Swiss Science Days in Zürich “Water for the Future”, ETHZ, November 9-10, 2011.
2010 Co-Organizer of an international symposium “Oxidation processes in natural and technical aquatic systems” in honour of Jürg Hoigné’s 80 birthday, Eawag, May 21, 2010.
2010 Co-Organizer of 23. Mülheimer Wassertechnisches Seminar “Möglichkeiten und Grenzen von oxidativen Prozessen in der Wasserreinhaltung”, March 11, 2010, IWW, Mülheim an der Ruhr
2008 Co-Organizer of the Eawag Infotag 2008 “Vom Gewässer ins Glas”, Sept. 12, 2008, Eawag, Dübendorf
2008 Organizing committee of Leading Edge Technology Conference (LET), Zürich, June 1-4, 2008.
2008 Co-organizer of Sino-Swiss workshop “Water Resources Management and Drinking Water Quality”, Harbin Institute of Technology, Harbin, China, January, 2008
2007 Organizer of Wave21 seminar on “New insights in the field of drinking water treatment”, Dübendorf, Sept. 14, 2007.
2007 Co-organizer of a symposium entitled “Sustainability in Water Supply: Advances in Oxidation Processes for Water Treatment” at ACS Spring conference, Chicago, March 25-29, 2007.
2006 Organizer of Wave21 seminar on “New developments of analytical methods for drinking water analysis”, Dübendorf, Sept. 15, 2006,
2005 Organizer of Wave21 seminar on “New applications of ozone in water treatment”, Sept. 23, 2005, Dübendorf
1999 Co-organizer of 200th Anniversary Symposium in honor of Ch. F. Schönbein - the discoverer of ozone, October 1999, Basel.
1995 Organizer of a symposium in honor of J. Hoigné, June, 1995, Dübendorf, Switzerland
1991 Co-organizer of the workshop "Chemodynamics of Groundwaters", November, 1991, Mont Sainte-Odile, France
John McKinney
Professor John McKinney received his Ph.D. from The Rockefeller University (New York, NY) in 1994 for studies on cell cycle regulation in
Saccharomyces cerevisiae
in the laboratory of Fred Cross. From 1995 to 1998, he was a postdoctoral fellow in the laboratory of William Jacobs at the Albert Einstein College of Medicine (Bronx, NY), where he studied mechanisms of persistence in
Mycobacterium tuberculosis
. In 1999, he returned to Rockefeller University to establish his own laboratory as an Assistant (1999-2004) and then Associate (2004-2007) Professor. In July 2007, the lab relocated to the Global Health Institute in the School of Life Sciences at the École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland, where McKinney is Professor and Head of the Laboratory of Microbiology and Microsystems (LMIC). Our research focuses on understanding the mechanistic basis of bacterial persistence in the context of host immunity and antimicrobial therapy, using
M. tuberculosis
as a "model" system.
Pierre Magistretti
Pierre J. Magistretti is an internationally-recognized neuroscientist who has made significant contributions in the field of brain energy metabolism. His group has discovered some of the cellular and molecular mechanisms that underlie the coupling between neuronal activity and energy consumption by the brain.
This work has considerable ramifications for the understanding of the origin of the signals detected with the current functional brain imaging techniques used in neurological and psychiatric research (see for example Magistretti et al, Science, 283: 496 497, 1999). He is the author of over 100 articles published in peer-reviewed journals.
He has given over 80 invited lectures at international meetings or at universities in Europe and North America, including the 2000 Talairach Lecture at the Functional Mapping of the Human Brain Conference. In November 2000 he has been a Mc Donnel Visiting Scholar at Washington University School of Medicine.
Pierre J. Magistretti is the President-Elect (2002 2004) of the Federation of European Neuroscience Societies (FENS) which has a membership of over 15000 European neuroscientists. He has been first president of the Swiss Society for Neuroscience (1997-1999) and the first Chairman of the Department of Neurosciences of the University of Lausanne (1996 1998).
Pierre J. Magistretti is Professor of Physiology (since 1988) at the University of Lausanne Medical School. He has been Vice-Dean of the University of Lausanne Medical School from 1996 to 2000. Pierre Magistretti, is Director of the Brain Mind Institute at EPFL and Director of the Center for Psychiatric Neuroscience of the University of Lausanne and CHUV. He is also Director of the NCCR SYNAPSY "the synaptic bases of mental diseases".
POSITIONS AND HONORS
MAIN POSITION HELD
1988-2004 Professor of Physiology, University of Lausanne Medical School
1996-2000 Vice-Dean for Preclinical Departments, University of Lausanne Medical School
2001-2004 Chairman, Department of Physiology, University of Lausanne Medical School
2004-present Professor and Director, Center for Psychiatric Neuroscience, Department of Psychiatry, University of Lausanne Medical School and Hospitals (UNIL-CHUV) (Joint appointment with EPFL)
2005-2008 Professor and Co-Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne (Joint appointment with UNIL-CHUV)
2007-present Chairman of the Scientific Advisory Board of Centre dImagerie Biomédicale (CIBM), an Imaging Consortium of the Universities, University Hospitals of Lausanne and Geneva and of Ecole Polytechnique Fédérale de Lausanne
2008-present Professor and Director, Brain Mind Institute, Federal Institute of Technology (EPFL), Lausanne Joint appointment with UNIL-CHUV)
2010-present Director, National Center for Competence in Research (NCCR)
The synaptic bases of mental diseases of the Swiss National Science Foundation
2010-present Secretary General, International Brain Research Organization (IBRO)
MAIN HONORS AND AWARDS
1997 Recipient of the Theodore-Ott Prize of the Swiss Academy of Medical Sciences
2001 Elected Member of Academia Europaea
2001 Elected Member of the Swiss Academy of Medical Sciences, ad personam
2002 Recipient of the Emil Kraepelin Guest Professorship, Max Planck Institute für Psychiatry, Münich
2006 Elected Professor at Collège de France, Paris, International Chair 2007-2008
2009 Goethe Award for Psychoanalytic Scholarship, Canadian Psychological Association
2011 Camillo Golgi Medal Award, Golgi Fondation
2011 Elected Member of the American College of NeuroPsychopharmacology (ACNP)
Christos Comninellis
Christos Comninellis, of Greek origin, born in 1945, received his Bachelor of Science in chemistry (distinction with honor) in 1970 from the University of Alexandria.
From 1971 to 1975, he worked as a chemist at the Institute of chemical engineering at the EPFL, where he achieved his PhD in technical sciences in 1979 for his research on the electrochemical fluorination of organic compounds in anhydrous hydrogen fluoride.
Appointed professor in 1996, he teaches at the Faculty of Basic Sciences (FSB) of the Swiss Federal Institute of Technology, Lausanne (EPFL)
Applied Chemistry.
Transport Phenomena.
Chemical and Electrochemical Technologies Related to the Environment.
Electrochemical Engineering.
He also holds a teaching position at the Haute Ecole Valaisanne Sion (HEVs).
His research work is focused on environmental electrochemistry, electrocatalysis, fuel cell and electrochemical promotion in catalysis. An applied research for the utilization of electrochemical techniques in industry for the protection of the environment is a constant concern within his activities. As a result, the collaboration with the industry enabled the development of oxidation processes with regeneration of the oxidant using a new type of bipolar electrochemical reactor.
Christos Comninellis has published over 170 scientific papers, directed 17 doctoral theses and holds 14 patents. He has participated in over 130 international symposia, giving five plenary lectures during the last five years. He has been president of the Evaluation Committee of the FSB since the beginning of 2004 and is member of the jury of the EPFL prize for outstanding PhD-thesis.