Concept
Early intervention in psychosis
Publications associées (30)
Neurocognition and NMDAR co-agonists pathways in individuals with treatment resistant first-episode psychosis: a 3-year follow-up longitudinal study
This study aims to determine whether 1) individuals with treatment-resistant schizophrenia display early cognitive impairment compared to treatment-responders and healthy controls and 2) N-methyl-D-aspartate-receptor hypofunction is an underlying mechanism ...
Springernature2024Transdiagnostic markers across the psychosis continuum: a systematic review and meta-analysis of resting state fMRI studies
Dimitri Nestor Alice Van De Ville, Farnaz Delavari
Psychotic symptoms are among the most debilitating and challenging presentations of severe psychiatric diseases, such as schizophrenia, schizoaffective, and bipolar disorder. A pathophysiological understanding of intrinsic brain activity underlying psychos ...
Frontiers Media Sa202420-years work investigating the shine-through paradigm in the schizophrenia spectrum: what is next?
Michael Herzog, Simona Adele Garobbio, Maya Roinishvili
In the past 20 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...
2023Multivariate patterns of disrupted sleep longitudinally predict affective vulnerability to psychosis in 22q11.2 Deletion Syndrome
Maude Schneider, Farnaz Delavari
22q11.2 deletion syndrome (22q11DS) contributes dramatically to increased genetic risk for psychopathology, and in particular schizophrenia. Sleep disorders, including obstructive sleep apnea (OSA), are also highly prevalent, making 22q11DS a unique model ...
ELSEVIER IRELAND LTD2023Exploring associations between diurnal cortisol, stress, coping and psychopathology in adolescents and young adults with 22q11.2 deletion syndrome
Maria del Carmen Sandi Perez, Olivia Zanoletti, Maude Schneider, Farnaz Delavari
Background: 22q11.2 deletion syndrome (22q11DS) is a neurogenetic condition associated to a high risk for psychiatric disorders, including psychosis. Individuals with 22q11DS are thought to experience increased levels of chronic stress, which could lead to ...
2022Long-term effects of early treatment with SSRIs on cognition and brain development in individuals with 22q11.2 deletion syndrome
Maude Schneider, Marie Schaer, Karin Bortolin
Cognitive deficits in individuals at risk of psychosis represent a significant challenge for research, as current strategies for symptomatic treatment are often ineffective. Recent studies showed that atypical cognitive development predicts the occurrence ...
SPRINGERNATURE2021The shine-through paradigm and the schizophrenia spectrum: a summary
Michael Herzog, Simona Adele Garobbio, Maya Roinishvili, Ophélie Gladys Favrod
In the past 10 years, our laboratory has proved the shine-through paradigm to be a very sensitive endophenotype for schizophrenia. The shine-through paradigm is a visual backward masking task, where the target is a vertical vernier followed by a 25-element ...
2021Sensorimotor Induction of Auditory Misattribution in Early Psychosis
Olaf Blanke, Andrea Serino, Alessandra Griffa, Fosco Bernasconi, Patric Hagmann, Kim Do, Roy Salomon, Giulio Rognini, Silvia Marchesotti, Pierre Progin
Dysfunction of sensorimotor predictive processing is thought to underlie abnormalities in self-monitoring producing passivity symptoms in psychosis. Experimentally induced sensorimotor conflict can produce a failure in bodily self-monitoring (presence hall ...
2020Unraveling neural and behavioral mechanisms of cognitive self-attenuation and alienation
The present thesis aimed at investigating behavioral and neural underpinnings of the mechanisms related to the different aspects of self-monitoring. The first aim was to study functional connectivity alterations related to the mechanisms accounting for the ...
EPFL2020