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Hemodynamic forces play an active role in vascular pathologies, particularly in relation to the localization of atherosclerotic lesions. It has been established that low shear stress combined with cyclic reversal of flow direction (oscillatory shear stress ...
A thermodynamic model, the Gibbs Free-Energy Minimization model (GFEMN), was used to simulate the partitioning of PM2.5 nitrate aerosol and nitric acid using highly time-resolved inorganic measurements collected at the Pittsburgh Air Quality Study during J ...
BACKGROUND: The peroxisome proliferator-activated receptor alpha (PPARalpha) plays an important role in the metabolism of lipoproteins and fatty acids, and seems to protect against the development of atherosclerosis. To evaluate the possible protective rol ...
Corticosteroid actions at the brain can modulate neural function and behavioral processes. Classic corticosteroid effects are mediated through intracellular receptors which act primarily by regulation of DNA transcription. However, an alternative nongenomi ...
The spontaneous locomotor behavior of rats receiving subcutaneous administration of either acidic or basic fibroblast growth factors was recorded in an activity cage. We report that doses between 1 and 100 micrograms/kg significantly decreased the horizont ...
We report in this paper on the electrochemical formation of nickel tetrasulfonated phthalocyanine (NiTSPc) based films on bulk Pt disk microelectrodes (diameter d = 50 μm) and thin-film Pt microdisk (diameter d = 10 μm) arrays for the realisation of Pt bas ...
Synthetic boron-doped diamond (BDD) thin film electrodes were tested for the electrogeneration of silver(II). In nitric acid, the kinetics of the silver(I)/silver(II) couple were studied by cyclic voltammetry. The results demonstrate that silver(II) can be ...
Intracellular reduction-oxidation status is increasingly recognized as a primary regulator of cellular growth and development. The relative reduction-oxidation state of the cell depends primarily on the precise balance between concentrations of reactive ox ...
In the central nervous system, nitric oxide has been proposed to be a retrograde messenger mediating learning and synaptic plasticity. Since only pretraining injections of nitric oxide synthesis inhibitors were shown to impair learning, we examined the pos ...
Mice with a disruption of the IFN-gamma receptor alpha-chain gene (IFN-gamma R alpha o/o mice) were found to be significantly more sensitive than their wild-type counterparts to induction of the anti-CD3-induced disease syndrome. Specifically, when given a ...
