Concept

Probabilistic risk assessment

Publications associées (84)

Probabilistic mechanics-based loss scenarios for school buildings in Basel (Switzerland)

Pierino Lestuzzi, Clotaire Michel, Pia Hannewald

Developing earthquake scenarios for cities in areas with a moderate seismicity is a challenge due to the limited amount of available data, which is a source of large uncertainties. This concerns both the seismic hazard, for which only recordings for small ...

2017

Accumulation in fed-batch reactor with multiple reaction scheme

Charles Ibrahim Guinand

Nowadays, the fine chemical industry requires increasingly faster time-to-market as well as economically efficient and safe processes. In addition, the growing product variety needs more versatile production plants able to produce from small amounts up to ...

EPFL2017

Altitude: architecture et environnement de haute montagne

Estelle Lépine

At the centre of the research is the preservation of the countryside which is highlighted and studied through an architectural approach which focuses on cabins in the high mountains. The projects must reflect upon territorial, global and sustainable aspect ...

EPFL2016

Alternative Approaches to Vertebrate Ecotoxicity Tests in the 21st Century: A Review of Developments Over the Last 2 Decades and Current Status

Kristin Schirmer

The need for alternative approaches to the use of vertebrate animals for hazard assessment of chemicals and pollutants has become of increasing importance. It is now the first consideration when initiating a vertebrate ecotoxicity test, to ensure that unne ...

Wiley-Blackwell2016

Levels of 48 pesticides in vegetables and water and evaluation of health risk resulting from dietary intake in gardening areas in Burkina Faso

Luiz Felippe De Alencastro, Edouard René Gilbert Lehmann

Exceedance of MRLs might induce a risk for the consumers and limits the opportunities of exportation for a sector identified by the authorities as having a great potential for the fight against poverty. In the same way, levels of some water samples exceed ...

2016

Joint applicability test of software for laboratory assessment and risk analysis

Thierry Meyer

Most of the available risk management methods are not directly applicable to academic research laboratories. One solution to systematically perform risk analyses in this environment is the Laboratory Assessment and Risk Analysis (LARA) method. This method ...

Elsevier2016

Silver nanoparticle-protein interactions in intact rainbow trout gill cells

Kristin Schirmer, Laura Sigg, Renata Behra, Yang Yue

Upon contact with biota, nanoparticles can bind to proteins, which coat the nanoparticles and form a nanoparticle-protein corona. Knowledge of corona proteins is therefore important for a mechanistic understanding of how nanoparticles interact with biomole ...

Royal Soc Chemistry2016

Analysis and Design of Metabolic Engineering and Synthetic Biology Strategies using Large Scale Dynamic Models of Metabolism

Vassily Hatzimanikatis, Ljubisa Miskovic, Georgios Fengos

Systematic analysis for the redirection of carbon flux in metabolite-producing microorganisms requires the comprehensive understanding of their complex metabolic processes. The use of large-scale dynamic models of metabolism plays key role in the understan ...

2016

Analysis and Design of Metabolic Engineering and Synthetic Biology Strategies using Large Scale Dynamic Models of Metabolism

Vassily Hatzimanikatis, Ljubisa Miskovic, Georgios Fengos

2016

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: I. Challenges and research needs in ecotoxicology

Kristin Schirmer

To elucidate the effects of chemicals on populations of different species in the environment, efficient testing and modeling approaches are needed that consider multiple stressors and allow reliable extrapolation of responses across species. An adverse out ...

Pergamon-Elsevier Science Ltd2015

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