Concept
Synthetic cannabinoids
Publications associées (32)
The Development of Aptamer-Coupled Microelectrode Fiber Sensors (apta-?FS) for Highly Selective Neurochemical Sensing
The selective and sensitive sensing of neurochemicals is essential to decipher in-brain chemistry underlying brain pathophysiology. The recent development of flexible and multifunctional polymer-based fibers has been shown useful in recording and modulatin ...
AMER CHEMICAL SOC2023Synthetic Receptors with Micromolar Affinity for Chloride in Water
Kay Severin, Farzaneh Fadaei Tirani, Damien Wen Chen, Cesare Berton, Sylvain Alexandre Marie Sudan
A water-soluble coordination cage was obtained by reaction of Pd(NO3)2 with a 1,3-di(pyridin-3-yl)benzene ligand featuring a short PEG chain. The cavity of the metal-organic cage contains one nitrate anion, which is readily replaced by chloride. The appare ...
Wiley2023Development of a novel Chimeric Antigen Receptor (CAR) for its use in Natural Killer (NK) cells for cancer treatment and beyond
The use of CAR technologies has revolutionized cancer treatment. Their unprecedented efficacy against B cell malignancies has opened the doors for a lot of excitement and research in the field. These synthetic receptors are composed of an antigen recogniti ...
EPFL2023Deciphering the molecular events leading to the global restoration of the chromatin landscape during mitotic exit
Two fundamental properties of embryonic stem cells (ESCs) are their ability to self-renew and differentiate into all somatic cell types. Maintenance of their identity faces major challenges when transitioning through mitosis, as most DNA-binding proteins a ...
EPFL2023Expanding computational biochemistry towards complex and non-natural compounds
In the beginning was the metabolism. The biochemical processes that make life possible transformed the soup of chemicals into the life on Earth we know today. Since then, living organisms have evolved, and life on Earth has become more complex. Living orga ...
EPFL2023Novel High-Throughput Fluorescence-Based Assay for the Identification of Nematocidal Compounds That Target the Blood-Feeding Pathway
Gerardo Turcatti, Marc Chambon, Anthony Marchand, Nicola Harris, Tiffany Babette Angélique Bouchery, Mati André Marie Moyat
Hookworm infections cause a neglected tropical disease (NTD) affecting ~740 million people worldwide, principally those living in disadvantaged communities. Infections can cause high morbidity due to their impact on nutrient uptake and their need to feed o ...
2022Vacuum Circuit Breaker Closing Time Key Moments Detection via Vibration Monitoring: A Run-to-Failure Study
Olga Fink, Gaëtan Michel Frusque
Circuit breakers (CBs) play an important role in modern society because they make the power transmission and distribution systems reliable and resilient. Therefore, it is important to maintain their reliability and to monitor their operation. A key to ensu ...
2022Monitoring of Priority Substances in Sediments of Switzerland
Florian Frédéric Vincent Breider, Benoît Jean Dominique Ferrari, Maria del Carmen Casado Martinez
In Switzerland, surface waters are protected by the Swiss Water Protection Ordinance (OEaux) which stipulates that the water quality shall be such that: "the water, suspended matter and sediments contain no persistent synthetic substances to ensure the pro ...
2020Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane
Patrick Daniel Barth, Mahdi Hijazi
The D2 dopamine receptor (DRD2) is a therapeutic target for Parkinson's disease(1)and antipsychotic drugs(2). DRD2 is activated by the endogenous neurotransmitter dopamine and synthetic agonist drugs such as bromocriptine(3), leading to stimulation of G(i) ...
NATURE PUBLISHING GROUP2020Quantification of THC in Cannabis plants by fast-HPLC-DAD: A promising method for routine analyses
Christophe Roussel, Céline Burnier
Nowadays, Gas Chromatography Mass Spectrometry (GC-MS) is mainly used in forensic sciences but suffers from limitations when the analysed compounds are thermally instable as it is the case for THC-A (Tetrahydrocannabinolic Acid) which is converted into Del ...
ELSEVIER SCIENCE BV2019