Publications associées à Agent innervant

High-content, arrayed compound screens with rhinovirus, influenza A virus and herpes simplex virus infections

Viruses are genetically and structurally diverse, and outnumber cells by orders of magnitude. They can cause acute and chronic infections, suppress, or exacerbate immunity, or dysregulate survival and growth of cells. To identify chemical agents with pro- ...

2022

Solid-phase peptide synthesis on disulfide-linker resin followed by reductive release affords pure thiol-functionalized peptides

Christian Heinis, Zsolt Bognár, Alexander Lund Nielsen, Manuel Leonardo Merz, Ganesh Kumar Mothukuri, Peter Matei Frisius Pânzar

Thiol groups are suitable handles for site-selectively modifying, immobilizing or cyclizing individual peptides or entire peptide libraries. A limiting step in producing the thiol-functionalized peptides is the chromatographic purification, which is partic ...

2022

A releasable disulfide-linked peptide tag facilitates the synthesis and purification of short peptides

Christian Heinis, Alessandro Zorzi, Yu Teng Wu, Jack Peter Christopher Williams

Combinatorial cyclization of hundreds to thousands of random linear peptides by structurally diverse chemical linkers offers access to large macrocyclic compound libraries. A bottleneck in the development of such libraries is the preparation of large numbe ...

Royal Society of Chemistry2020

Towards an Adaptive Upper Limb Rehabilitation Game with Tangible Robots

Pierre Dillenbourg, Friedhelm Christoph Hummel, Pablo Maceira Elvira, Wafa Monia Benkaouar Johal, Maximilian Jonas Wessel, Ayberk Özgür, Louis Pierre Faucon, Arzu Güneysu Özgür, Andéol Geoffroy Cadic-Melchior

A key feature of a successful game is its ability to provide the player with an adequate level of challenge. However, the objective of difficulty adaptation in serious games is not only to maintain the player’s motivation by challenging, but also to ensure ...

2019

Electronic metal–organic framework sensors

Kyriakos Stylianou, Arunraj Chidambaram

Metal–organic frameworks (MOFs), a class of crystalline and porous materials, are synthesized through the self-assembly of organic ligands and inorganic metal nodes (ions or clusters). For the past few years, MOFs have been in the limelight due to their st ...

2018

Intrafascicular electrode implant

Silvestro Micera, Stanisa Raspopovic, Francesco Maria Petrini

An implantable device for intrafascicular stimulation and/or sensing of a peripheral nerve, including a blocking element adapted for wrapping a nerve, comprising an access point and an exit point, and an electrode adapted to traverse the blocking element v ...

2018

Towards an (∞,2)-category of homotopy coherent monads in an ∞-cosmos

Dimitri Zaganidis

This thesis is part of a program initiated by Riehl and Verity to study the category theory of (infinity,1)-categories in a model-independent way. They showed that most models of (infinity,1)-categories form an infinity-cosmos K, which is essentially a cat ...

EPFL2017

Elicitation and Aggregation of Crowd Information

Goran Radanovic

This thesis addresses challenges in elicitation and aggregation of crowd information for settings where an information collector, called center, has a limited knowledge about information providers, called agents. Each agent is assumed to have noisy private ...

EPFL2016