Concept

Brain simulation

Publications associées (311)

Noise facilitation in associative memories of exponential capacity

Mohammad Amin Shokrollahi, Amin Karbasi, Amir Hesam Salavati

Recent advances in associative memory design through structured pattern sets and graph-based inference al- gorithms have allowed reliable learning and recall of an exponential number of patterns. Although these designs correct external errors in recall, th ...

Mit Press2014

Interactive Learning from Unlabeled Instructions

Inaki Asier Iturrate Gil

Interactive learning deals with the problem of learning and solving tasks using human instructions. It is common in human-robot interaction, tutoring systems, and in human-computer interfaces such as brain-computer ones. In most cases, learning these tasks ...

2014

The In-Silico Neocortical Microcircuit

Michael Reimann

The neocortex is one of the most important brain regions, occupying more than 80% of the brain volume in mammals and contributing massively to its capability of perceiving and interpreting then environment. While it has been extensively studied, it is stil ...

EPFL2014

Multi-modal assessment of long-term erythropoietin treatment after neonatal hypoxic-ischemic injury in rat brain

Rolf Gruetter, Yohan Van de Looij

Erythropoietin (EPO) has been recognized as a neuroprotective agent. In animal models of neonatal brain injury, exogenous EPO has been shown to reduce lesion size, improve structure and function. Experimental studies have focused on short course treatment ...

Public Library of Science2014

MRS glucose mapping and PET joining forces: Re-evaluation of the lumped constant in the rat brain under isoflurane anaesthesia

Rolf Gruetter, Hongxia Lei, João Miguel das Neves Duarte, Malte Alf

Although numerous positron emission tomography (PET) studies with ((8) F-fluoro-deoxyglucose) FDG have reported quantitative results on cerebral glucose kinetics and consumption, there is a large variation between the absolute values found in the literatur ...

Wiley-Blackwell2014

Seven challenges for neuroscience

Henry Markram

Although twenty-first century neuroscience is a major scientific enterprise, advances in basic research have not yet translated into benefits for society. In this paper, I outline seven fundamental challenges that need to be overcome. First, neuroscience h ...

2013

Computational Neuroscience Breakthroughs Through Innovative Data Management

Anastasia Ailamaki, Thomas Heinis, Farhan Tauheed, Sadegh Heyrani Nobari, Laurynas Biveinis

Simulations have become key in many scientific disciplines to better understand natural phenomena. Neuroscientists, for example, build and simulate increasingly fine grained models (including subcellular details, e.g., neurotransmitter) of the neocortex to ...

2013

Graph theory reveals dysconnected hubs in 22q11DS and altered nodal efficiency in patients with hallucinations

Jean-Philippe Thiran, Leila Cammoun, Marie Schaer

Schizophrenia is postulated to be the prototypical dysconnection disorder, in which hallucinations are the core symptom. Due to high heterogeneity in methodology across studies and the clinical phenotype, it remains unclear whether the structural brain dys ...

Frontiers Research Foundation2013

Neuroscience thinks big (and collaboratively)

Henry Markram

Despite cash-strapped times for research, several ambitious collaborative neuroscience projects have attracted large amounts of funding and media attention. In Europe, the Human Brain Project aims to develop a large-scale computer simulation of the brain, ...

Nature Publishing Group2013

Synaptic Computation and Sensory Processing in Neocortical Layer 2/3

Carl Petersen, Sylvain Crochet

Computations in neocortical circuits are predominantly driven by synaptic integration of excitatory glutamatergic and inhibitory GABAergic inputs. New optical, electrophysiological, and genetic methods allow detailed in vivo investigation of the superficia ...

Cell Press2013

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