Johan AuwerxJohan Auwerx is Professor at the École Polytechnique Fédérale in Lausanne, Switzerland, where he occupies the Nestle Chair in Energy Metabolism. Dr. Auwerx has been using molecular physiology and systems genetics to understand metabolism in health, aging and disease. Much of his work focused on understanding how diet, exercise and hormones control metabolism through changing the expression of genes by altering the activity of transcription factors and their associated cofactors. His work was instrumental for the development of agonists of nuclear receptors - a particular class of transcription factors - into drugs, which now are used to treat high blood lipid levels, fatty liver, and type 2 diabetes. Dr. Auwerx was amongst the first to recognize that transcriptional cofactors, which fine-tune the activity of transcription factors, act as energy sensors/effectors that influence metabolic homeostasis. His research validated these cofactors as novel targets to treat metabolic diseases, and spurred the clinical use of natural compounds, such as resveratrol, as modulators of these cofactor pathways.
Johan Auwerx was elected as a member of EMBO in 2003 and is the recipient of a dozen of international scientific prizes, including the Danone International Nutrition Award, the Oskar Minkowski Prize, and the Morgagni Gold Medal. His work is highly cited by his peers with a h-factor of over 100. He is an editorial board member of several journals, including Cell Metabolism, Molecular Systems Biology, The EMBO Journal, Journal of Cell Biology, Cell, and Science. Dr. Auwerx co-founded a handful of biotech companies, including Carex, PhytoDia, and most recently Mitobridge, and has served on several scientific advisory boards.
Dr. Auwerx received both his MD and PhD in Molecular Endocrinology at the Katholieke Universiteit in Leuven, Belgium. He was a post-doctoral research fellow in the Departments of Medicine and Genetics of the University of Washington in Seattle.
Patrick Daniel BarthProfessor Patrick Barth is Associate Professor at EPFL and Adjunct Associate Professor at Baylor College of Medicine, Houston, TX, USA. He received training in Physics, Chemistry and Biology (University of Paris, ENS) in France and performed his PhD at the Commissiariat a l'Energie Atomique in Saclay, France on structure/function studies of membrane proteins (photosystem I) using biochemical and biophysical experimental techniques. He carried out postdoctoral studies at University of California at Berkeley with Tom Alber on computational development for calculating protein electrostatics and designing de novo selective peptide inhibitors of cellular protein interactions. He then went to the University of Washington as a postdoctoral fellow and instructor in David Baker's laboratory to develop computational techniques in the software Rosetta for predicting and designing membrane protein structures. He started his independent career and received tenure at Baylor College of Medicine. He will continue at EPFL to marry computation and experiment for understanding the molecular determinants of signal transduction, as well as modeling and designing membrane proteins with novel functions for various synthetic biology and therapeutic applications.
Jean-Claude BünzliJean-Claude Bünzli was born in 1944. He earned a degree in chemical engineering in 1968 and a PhD in 1971 (Swiss Federal Institute of Technology, Lausanne) for his work on the kinetic behaviour of Nb and Ta pentachloride adducts. He spent two years at the University of British Columbia as a teaching postdoctoral fellow (photoelectron spectroscopy) and one year at the Swiss Federal Institute of Technology in Zürich (physical organic chemistry).
Positions
He was appointed assistant-professor at the University of Lausanne in 1974 and started a research program on the spectrochemical properties of f-elements. He was promoted as a full professor of inorganic and analytical chemistry in 1980. He transferred to EPFL in 2001 where he directed the Laboratory of Lanthanide Supramolecular Chemistry until 2010.
From 2009 to 2013, he was World Class University Professor at Korea University (South Korea) helping developing a new research center for photovoltaics. In 20154-2015 he acted as visiting professor at FJIRSM (Fuzhou, Fujian), a laboratory of the Chinese Academy of Sciences.
He presently holds the Dr Kennedy Wong Distinguished Visiting Professorship at Hong Kong Baptist University (3 months/year) and a position as Distinguished Scholar at University of Technology, Sydney (NSW, Australia, 1 month/year).
Administrative and reviewer duties
He acted as the elected Dean of the Faculty of Sciences (1990-1991) and as one of the elected Vice-Rectors of the University (1991-1995), in charge of students' affairs and of research programs in the field of biomedical sciences. He held a position of invited professor at the Université Louis Pasteur, Strasbourg in 1996 and at the Science University of Tokyo in 1998. In 1989, he founded the European Rare Earths and Actinide Society which coordinate international conferences in the field (cf. http://ereswww.epfl.ch).
He served as a World Bank Project Specialist within the framework of the Chinese Provincial Universities Development Project (Northwest China, 1989) and as a member of a Panel in charge of evaluating chemical research at Norwegian universities (1997). In 2001, he was hired as "Peer leader" for the evaluation of the Swiss universities of applied sciences. In 2005, he acted as a member of the "Physical Inorganic Panel" of the Science Foundation of Ireland and in 2006 he was nominated to the "Chemistry Panel" of the same foundation.
He is a member of the Editorial Board of Spectroscopy Letters, associate editor-in-chief of the Journal of Rare Earths, and senior editor of the Handbook on the Physics and Chemistry of Rare Earths (54 volumes published to date).
Teaching
Regarding teaching, he has directed the joint project of the universities of Geneva, Lausanne, Neuchâtel and Fribourg "General chemistry for students enrolled in a life sciences curriculum", within the frame of the "Swiss virtual campus", a program sponsored by the Conference of Swiss universities and the Swiss federal office for science and education (2000-2004). Web site: http://chimge@epfl.ch
Research
His research is centered on lanthanide luminescent molecular and supramolecular edifices, with main applications in biology & medicine. He is the author or the co-author of 350 research papers, 260 contributed communications and has presented 285 invited conferences, seminars, and courses. He has collected >22800 citations (h-index 72). Nicolai CramerNicolai Cramer est né à Stuttgart, en Allemagne ; il a étudié la chimie à l'université de Stuttgart, où il a obtenu son diplôme en 2003, et son doctorat en 2005 sous la direction du professeur Sabine Laschat. Après un stage de recherche à l'université d'Osaka, au Japon, en 2006 il a rejoint le groupe du professeur Barry M. Trost à l'université de Stanford en tant que postdoc. A partir de 2007, il a travaillé sur son habilitation à l'ETH Zurich sous la direction du Professeur Erick M. Carreira et a reçu la venia legendi en 2010. En 2010, il a été nommé comme professeur assistant à l'EPF de Lausanne et a été promu professeur associé en 2013 et professeur ordinaire en 2015. Son principal programme de recherche englobe les transformations énantiosélectives catalysées par des métaux et leur mise en œuvre pour la synthèse de molécules biologiquement actives.Profile (Angew. Chem. Int. Ed.)
CV
Henning Paul-Julius StahlbergPositions:
Since 2020 Prof. Physics, IPHYS, SB, EPFL, Switzerland 2009 – 2021 Prof. Structural Biology, Biozentrum, University Basel, Switzerland
2009 – 2010 Adj. Assoc. Prof. Molecular & Cellular Biology, UC Davis, CA, USA
2007 – 2009 Assoc. Prof. Molecular & Cellular Biology, UC Davis, CA, USA
2003 – 2007 Assist. Prof. Molecular & Cellular Biology, UC Davis, CA, USA
Education: 2002 Habilitation, Biozentrum, University Basel, Switzerland 1997 – 2003 Postdoctoral Fellow, Biozentrum, University Basel, Switzerland 1992 – 1997 PhD Student, EPFL, Lausanne, Switzerland 1990 – 1991 Diploma Thesis in Solid State Physics, TU Berlin, Germany 1987 – 1993 Study of Physics, TU Berlin, Germany Selected Awards & Honors: 2009 W.M.Keck Award 2004 CAREER award, NSF, USA 2002 Habilitation, University Basel, Switzerland Selected Memberships: 2008 – 2013 Chancellor’s Fellow Award, UC Davis, CA, USA 2004 – 2009 Faculty of 1000 Since 1992 Swiss Society for Optics and Microscopy (SSOM)
Ursula RöthlisbergerU. Röthlisberger was born in Solothurn (Switzerland). In 1988 she made her diploma in Physical Chemistry in the group of Prof. Ernst Schumacher at the University of Berne (Switzerland). Her Ph.D. thesis was done in collaboration with Dr. Wanda Andreoni at the IBM Zurich Research Laboratory in Rüschlikon. After finishing her Ph.D in 1991 she spent some time as a postdoctoral research assistant at the IBM Research Lab. From 1992-1995 she was a postdoctoral research assistant in the group of Prof. Michael L. Klein at the University of Pennsylvania in Philadelphia (USA). In 1994 she was awarded an advanced researcher fellowship (Profil 2) from the Swiss National Science Foundation. Before starting her Profile 2-fellowship she spent another year as postdoctoral research assistant in the group of Prof. Michele Parrinello at the Max-Planck-Institute for Solid State Physics in Stuttgart, Germany. In 1996 she moved as Profile 2-fellow to the ETH in Zurich, hosted by the group of Prof. Wilfred F. van Gunsteren. In 1997 she became Assistant Professor of Computer-Aided Inorganic Chemistry at the ETH Zurich.