Concept
Polymorphisme de longueur des fragments amplifiés
Publications associées (4)
Lentiviral-mediated gene transfer into haematopoietic stem cells
OBJECTIVES: Lentiviral vectors can transduce nondividing cells. As most haematopoietic stem cells (HSCs) are nondividing in vivo, lentiviral vectors are promising viral vectors to transfer genes into HSCs. DESIGN AND SETTING: We have used HIV-1 based lenti ...
Wiley-Blackwell2001Sampling the genomic pool of protein tyrosine kinase genes using the polymerase chain reaction with genomic DNA
The polymerase chain reaction (PCR), with cDNA as template, has been widely used to identify members of protein families from many species. A major limitation of using cDNA in PCR is that detection of a family member is dependent on temporal and spatial pa ...
1998Integration and stability of CHO amplicons containing plasmid sequences
Fluorescence in situ hybridization (FISH, 15) and high density, non-selective long term perfusion culture were used to study aspects of genetic stability and productivity in recombinant CHO cells. We analysed the distribution and structure of recombinant a ...
1992