Publications associées à Immunothérapie

A niche role for periostin and macrophages in glioblastoma

Michele De Palma, Mario Leonardo Squadrito

Macrophages facilitate tumour progression, but it is unclear whether this capability is influenced by tumour-initiating cells. Glioblastoma stem cells are now shown to secrete periostin, a matrix protein that recruits protumoral macrophages and enhances gl ...

Nature Publishing Group2015

A single epidermal stem cell strategy for safe ex vivo gene therapy

Graham Knott, Jacques Rougemont, Yann Barrandon, Ariane Rochat, Andrea Zaffalon, Nicolas Grasset, Stéphanie Danièle Hélène Droz-Georget, Sara Benmohammed, Emmanuelle Savioz-Dayer, Alessandra Recchia

There is a widespread agreement from patient and professional organisations alike that the safety of stem cell therapeutics is of paramount importance, particularly for ex vivo autologous gene therapy. Yet current technology makes it difficult to thoroughl ...

Wiley Open Access2015

Bioanalytical methods for food allergy diagnosis, allergen detection and new allergen discovery

Hubert Girault, Natalia Gasilova

For effective monitoring and prevention of the food allergy, one of the emerging health problems nowadays, existing diagnostic procedures and allergen detection techniques are constantly improved. Meanwhile, new methods are also developed, and more and mor ...

Future Sci Ltd2015

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression

Michele De Palma, Mario Leonardo Squadrito

The immunosuppressive tumor microenvironment represents a major hurdle to cancer therapy. We developed a gene transfer strategy into hematopoietic stem cells (HSCs) to target transgene expression to tumor-infiltrating monocytes/macrophages. Using a combina ...

2014

Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes

Jeffrey Alan Hubbell, Melody Swartz, Alexandre de Titta, Pedro Romero, Marie Ballester, Laura Jeanbart, Patricia Corthésy Henrioud

The sentinel or tumor-draining lymph node (tdLN) serves as a metastatic niche for many solid tumors and is altered via tumor-derived factors that support tumor progression and metastasis. tdLNs are often removed surgically, and therapeutic vaccines against ...

Amer Assoc Cancer Research2014

Immunomodulatory Roles of Lymphatic Vessels in Cancer Progression

Melody Swartz

Lymphatic vessels in the tumor microenvironment are known to foster tumor metastasis in many cancers, and they can undergo activation, hyperplasia, and lymphangiogenesis in the tumor microenvironment and in the tumor-draining lymph node. The mechanism unde ...

Amer Assoc Cancer Research2014

Emerging roles of lymphatic endothelium in regulating adaptive immunity

Melody Swartz, Catherine Mary Card

Emerging research on the roles of stromal cells in modulating adaptive immune responses has included a new focus on lymphatic endothelial cells (LECs). LECs are presumably the first cells that come into direct contact with peripheral antigens, cytokines, d ...

American Society for Clinical Investigation2014

Steady-State Antigen Scavenging, Cross-Presentation, and CD8(+) T Cell Priming: A New Role for Lymphatic Endothelial Cells

Marcela Rincón-Restrepo, Efthymia Vokali, Melody Swartz, Sachiko Hirosue, Amanda Waite Lund, Patricia Corthésy Henrioud, Vidya Raghavan

Until recently, the known roles of lymphatic endothelial cells (LECs) in immune modulation were limited to directing immune cell trafficking and passively transporting peripheral Ags to lymph nodes. Recent studies demonstrated that LECs can directly suppre ...

Amer Assoc Immunologists2014

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Immunothérapie

A niche role for periostin and macrophages in glioblastoma

A single epidermal stem cell strategy for safe ex vivo gene therapy

Bioanalytical methods for food allergy diagnosis, allergen detection and new allergen discovery

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression

Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes

Immunomodulatory Roles of Lymphatic Vessels in Cancer Progression

Emerging roles of lymphatic endothelium in regulating adaptive immunity

Mucosal immune responses following intestinal nematode infection

Steady-State Antigen Scavenging, Cross-Presentation, and CD8(+) T Cell Priming: A New Role for Lymphatic Endothelial Cells

Exploring new therapeutic strategies for Huntington's Disease

Graph Chatbot

Chattez avec Graph Search

Bioanalytical methods for food allergy diagnosis, allergen detection and new allergen discovery

Mucosal immune responses following intestinal nematode infection

Exploring new therapeutic strategies for Huntington's Disease

A single epidermal stem cell strategy for safe ex vivo gene therapy

A niche role for periostin and macrophages in glioblastoma

Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression

Emerging roles of lymphatic endothelium in regulating adaptive immunity

Steady-State Antigen Scavenging, Cross-Presentation, and CD8(+) T Cell Priming: A New Role for Lymphatic Endothelial Cells

Enhancing Efficacy of Anticancer Vaccines by Targeted Delivery to Tumor-Draining Lymph Nodes

Immunomodulatory Roles of Lymphatic Vessels in Cancer Progression