Concept
Élimination de β-hydrure
Publications associées (16)
Synthetic methodologies for C-C and C-N bond formation involving alkyl radicals
C-C and C-N bonds are some of the most common structures in molecules ranging from drugs to catalysts and to food additives. Many coupling reactions were developed to form these types of bonds with excellent selectivity and good performance. Still, the syn ...
EPFL2020Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes
Qian Wang, Jieping Zhu, Ruben Omar Torres Ochoa, Zhaodong Li
Transition metal catalyzed Sonogashira cross-coupling of terminal alkynes with aryl(vinyl) (pseudo)halides has been successfully extended to alkyl halides for the synthesis of functionalized internal alkynes. The direct alkynylation of remote unfunctionali ...
2020Small Molecule Activation by Multimetallic Uranium Complexes
The development of new processes for the selective and sustainable transformation of abundant small molecules constitutes one of the major research areas in inorganic and organometallic chemistry. These molecules as CO2, CO, N2 and H2 are abundant reservoi ...
EPFL2019A β-Carbon elimination strategy for convenient in situ access to cyclopentadienyl metal complexes
Nicolai Cramer, Matthew Wodrich, Benoît Daniel Bertrand Audic, Gints Smits
The electronic and steric properties of tailored cyclopentadienyl (Cp) ligands are powerful handles to modulate the catalytic properties of their metal complexes. This requires the individual preparation, purification and storage of each ligand/metal combi ...
2017Nickel-catalyzed Hydrosilylation of Alkenes and Transition-Metal-Free Intermolecular α-C-H Amination of Ethers
Transition-metal-catalyzed hydrosilylation of olefins is one of the most important methods for the preparation of organosilicon compounds, which have broad applications in both synthetic and material chemistry. For decades, precious metals, principally pla ...
EPFL2016