Concept
Maximum life span
Publications associées (55)
Detecting the metabolism of individual yeast mutant strain cells when aged, stressed or treated with antioxidants with diamond magnetometry
Free radicals play a key role in the ageing process. However, free radicals are small, reactive and short lived and thus challenging to measure. We utilize a new technique called diamond magnetometry for this pur-pose. We make use of nitrogen vacancy cente ...
ELSEVIER SCI LTD2023Towards learning-based image compression for storage on DNA support
Touradj Ebrahimi, Michela Testolina
The demand for data storage has grown exponentially over the past decades. Current archival solutions have significant shortcomings, such as high resource requirements and a lack of sufficient longevity. In contrast, research on DNA-based storage has been ...
2023Analysis of the influence of errors in DNA-based image coding
Touradj Ebrahimi, Michela Testolina
In the last decade, DNA has been increasingly investigated as an alternative medium for cold data storage, presenting several advantages over standard hard drives such as a higher density, longer lifespan and lower energy consumption. However, such coding ...
2023Inhibiting de novo ceramide synthesis restores mitochondrial and protein homeostasis in muscle aging
Johan Auwerx, Xiaoxu Li, Mario Romani, Tanes Imamura de Lima, Sandra Rodriguez Lopez, Jean-David Horacio Morel, Hao Li, Martin Rainer Wohlwend, Pirkka-Pekka Untamo Laurila, Ludger Jan Elzuë Goeminne, Barbara Moreira Crisol, Changmyung Oh, Dohyun Park
Disruption of mitochondrial function and protein homeostasis plays a central role in aging. However, how these processes interact and what governs their failure in aging remain poorly understood. Here, we showed that cer- amide biosynthesis controls the de ...
AMER ASSOC ADVANCEMENT SCIENCE2023Human mortality at extreme age
We use a combination of extreme value statistics, survival analysis and computer-intensive methods to analyse the mortality of Italian and French semi-supercentenarians. After accounting for the effects of the sampling frame, extreme-value modelling leads ...
ROYAL SOC2021