Publications associées à Organoiron chemistry

Complexation Strategies towards Challenging Group 9 Metal Cyclopentadienyl Scaffolds

Cyclopentadienyl (Cp) metal complexes and their chiral counterparts (CpX) have enabled the development of challenging C-H activation transformations. While major progresses were made in developing new chiral CpX complexes and exploring their reactivity, th ...

EPFL2023

Synthesis of Chiral Cyclopentadienyl Complexes and Applications Towards C-H Functionalization

Benoît Daniel Bertrand Audic

Metal-catalysed C-H bond functionalization has received tremendous attention and developed rapidly over the past decades. Cyclopentadienyl (Cp) metal complexes and their asymmetric counterparts (CpX) are part of a central organometallic category empowering ...

EPFL2021

A Strategy to Conjugate Bioactive Fragments to Cytotoxic Diiron Bis(cyclopentadienyl) Complexes

Paul Joseph Dyson, Mouna Hadiji, Silvia Schoch, Sarah Alexandra Pais Pereira

A series of bioactive molecules were synthesized from the condensation of aspirin or chlorambucil with terminal alkynes bearing alcohol or amine substituents. Insertion of the resulting alkynes into the iron-carbyne bond of readily accessible diiron bis(cy ...

AMER CHEMICAL SOC2021

Reactivity and biological activity of N,N,S-Schiff-base rhodium pentamethylcyclopentadienyl complexes

Paul Joseph Dyson, Lucinda Kate Batchelor

Neutral piano-stool complexes of the general formula [(eta(5)-C5Me5)Rh(L-OR)] (R = Me, 1; R = Et, 2; R = Pe(i), 3) have been prepared in alcohols (methanol, 1; ethanol, 2; isopropanol, 3) from the Schiff-base 5-methyl-4-{(pyridin-2-ylmethylene)amino}-4H-1, ...

ELSEVIER SCIENCE SA2020

Structure and small molecule activation reactivity of a metallasilsesquioxane of divalent ytterbium

Rosario Scopelliti, Marinella Mazzanti, Aurélien René Willauer

The first metallasilsesquioxane of a divalent lanthanide, Yb{Cy7Si7O11(OSiMe3)}(THF),1, was synthesized and structurally characterized. The Cy7Si7O11(OSiMe3)(2-)ligands in1bind two Yb(ii) ions in a bridging mode. The dinuclear complex effects the two- ...

Royal Society of Chemistry2020

Diiron Complexes with a Bridging Functionalized Allylidene Ligand: Synthesis, Structural Aspects, and Cytotoxicity

Paul Joseph Dyson, Lucinda Kate Batchelor, Silvia Schoch

Regio- and stereoselective nucleophilic attack of cyanide (from NBu4CN) to cationic diiron vinyliminium compounds [Fe2Cp2(CO)(mu-CO){mu-eta(1):eta(3)-C-(R')C(R '')-CNMe2}]CF3SO3 ([1a-f]CF3SO3) affords the nitrile-aminoallylidene derivatives 2a-f in good to ...

AMER CHEMICAL SOC2020

Enantioselective C(sp(3))-C(sp(3)) cross-coupling of non-activated alkyl electrophiles via nickel hydride catalysis

Xile Hu, Runze Mao, Srikrishna Bera

Cross-coupling of two alkyl fragments is an efficient method to produce organic molecules rich in sp(3)-hybridized carbon centres, which are attractive candidate compounds in drug discovery. Enantioselective C(sp(3))-C(sp(3)) coupling is challenging, espec ...

2020

Anticancer Potential of Diiron Vinyliminium Complexes

Paul Joseph Dyson, Lucinda Kate Batchelor, Silvia Schoch

Although ferrocene derivatives have attracted considerable attention as possible anticancer agents, the medicinal potential of diiron complexes has remained largely unexplored. Herein, we describe the straightforward multigram-scale synthesis and the antip ...

WILEY-V C H VERLAG GMBH2019

CO2 and CO/H-2 Conversion to Methoxide by a Uranium(IV) Hydride

Rosario Scopelliti, Marinella Mazzanti, Marta Falcone

Here we show that a scaffold combining siloxide ligands and a bridging oxide allows the synthesis and characterization of the stable dinuclear uranium(IV) hydride complex [K-2{U(OSi((OBu)-Bu-t)(3))(3)(mu-O)(mu-H)(2)}], 2, which displays high reductive ...

2019

Carbon dioxide reduction by dinuclear Yb(ii) and Sm(ii) complexes supported by siloxide ligands

Marinella Mazzanti, Farzaneh Fadaei Tirani, Davide Toniolo

Two dinuclear homoleptic complexes of lanthanides(II) supported by the polydentate tris(tertbutoxy) siloxide ligand ([Yb2L4], 1-Yb and [Sm2L4], 1-Sm, (L = (OtBu)3SiO−)) were synthesized in 70–80% yield and 1-Sm was crystallographically characterized. 1-Yb ...

2019