Concept

Neutropénie

Publications associées (27)

A Quantitative Approach to Evaluate the Impact of Fluorescent Labeling on Membrane-Bound HIV-Gag Assembly by Titration of Unlabeled Proteins

The assembly process of the human immunodeficiency virus 1 (HIV-1) is driven by the viral polyprotein Gag. Fluorescence imaging of Gag protein fusions is widely performed and has revealed important information on viral assembly. Gag fusion proteins are com ...

Public Library Science2014

Role of the bile acid membrane receptor TGR5 in macrophages and metabolism

Mitsunori Nomura

Activation of the bile acid responsive G protein-coupled receptor TGR5 improves metabolic homeostasis via induction of energy expenditure and release of glucagon-like peptide-1 (GLP-1). The goal of my PhD work was to explore the role of macrophage TGR5 wit ...

EPFL2013

Lipopolysaccharide induces intestinal glucocorticoid synthesis in a TNFalpha-dependent manner

Kristina Schoonjans

Stringent control of immune responses in the intestinal mucosa is critical for the maintenance of immune homeostasis and prevention of tissue damage, such as observed during inflammatory bowel disease. Intestinal epithelial cells, primarily thought to form ...

2010

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

Anne Wilson

The activity of adult stem cells is essential to replenish mature cells constantly lost due to normal tissue turnover. By a poorly understood mechanism, stem cells are maintained through self-renewal while concomitantly producing differentiated progeny. He ...

2004

A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival

Steinunn Baekkeskov Hanahan

Background. Dendritic cells are potent antigen-presenting cells that bind allogeneic T cells. They are thus candidates for targeting immunoregulatory molecules to the alloreactive T cell compartment and suppressing the alloimmune response. Method. A dendri ...

Lippincott, Williams & Wilkins2000

Characterization of recombinant-derived granulocyte-colony stimulating factor (G-CSF)

Gerardo Turcatti

Human granulocyte colony-stimulating factor (G-CSF), and a mutant having a Ser for Cys substitution at residue 18 were produced in Escherichia coli strain W3110. About 60 mg of pure protein was obtained from 50 g of wet cells with a recovery of about 20%. ...

1988

Treatment of hairy cell leukemia with recombinant alpha interferon: I. Quantitative study of bone marrow changes during the first months of treatment

Michel Aguet

Seventeen patients with hairy cell leukemia (HCL) were treated with low doses of recombinant alpha interferon (IFN) for over 4 months. Marked improvement was observed in peripheral blood and bone marrow in 15 of 17 patients. Comparison of pretreatment valu ...

1986

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