Concept

Rhabdomyolyse

Publications associées (8)

Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure

BACKGROUND: Abnormalities in cardiac energy metabolism occur in heart failure (HF) and contribute to contractile dysfunction, but their role, if any, in HF-related pathologic remodeling is much less established. CK (creatine kinase), the primary muscle ene ...

LIPPINCOTT WILLIAMS & WILKINS2022

Polymeric Micelles Loading Proteins through Concurrent Ion Complexation and pH-Cleavable Covalent Bonding for In Vivo Delivery

Francesco Stellacci, Suiyang Liao

Protein drugs have great potential as targeted therapies, yet their application suffers from several drawbacks, such as instability, short half-life, and adverse immune responses. Thus, protein delivery approaches based on stimuli-responsive nanocarriers c ...

WILEY-V C H VERLAG GMBH2019

Extraction of QRS fiducial points from the ECG using adaptive mathematical morphology

Jean-Marc Vesin, Sasan Yazdani

QRS complex detection in the electrocardiogram (ECG) has been extensively investigated over the last two decades. Still, some issues remain pending due to the diversity of QRS complex shapes and various perturbations, notably baseline drift. This is especi ...

Academic Press Inc Elsevier Science2016

Ultrafast Tryptophan-to-Heme Electron Transfer in Myoglobins Revealed by UV 2D Spectroscopy

Majed Chergui, Frank van Mourik, Cristina Consani

Tryptophan is commonly used to study protein structure and dynamics, such as protein folding, as a donor in fluorescence resonant energy transfer (FRET) studies. By using ultra-broadband ultrafast two-dimensional (2D) spectroscopy in the ultraviolet (UV) a ...

American Association for the Advancement of Science2013

Ultrafast One- and Two-Dimensional UV Transient Absorption Spectroscopy of Haem Proteins

Cristina Consani

Proteins are dynamic macromolecules, which accomplish biological function driven by long-range interactions and global motions. While their biological function is often clear, little is known about the collective interactions which make these systems real ...

EPFL2012

Neuroprotective role of lactate after cerebral ischemia

Rolf Gruetter, Pierre Magistretti, Hongxia Lei, Jonathan Thevenet

It is well established that lactate can be used as an energy substrate by the brain by conversion to pyruvate and a subsequent oxidation in the mitochondria. Knowing the need for readily metabolizable substrates directly after ischemia and the protective e ...

2009

Brain glucose concentrations in healthy humans subjected to recurrent hypoglycemia

Rolf Gruetter, Anjali Kumar

Mechanisms responsible for hypoglycemia unawareness remain unknown. Previously, we found that patients with type 1 diabetes and hypoglycemia unawareness had increased brain glucose concentrations as measured by (1)H-magnetic resonance spectroscopy (MRS) co ...

Wiley-Blackwell2005

Defective host defence mechanisms in a family with hypocalciuric hypercalcaemia and coexisting interstitial lung disease

Johan Auwerx

An extensive in vitro investigation of the host defence system was performed in 11 sibs of a large kindred with unexplained combination of familial hypocalciuric hypercalcaemia (FHH), interstitial lung disease and increased susceptibility to respiratory in ...

1985

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