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This paper considers vessel scheduling with pilotage and tugging constraints in berthing operations with channel restrictions at seaports. To our knowledge, pilotage and tugging requirements have not been simultaneously considered in the literature. This w ...
A series of four drug release formulations based on 5-fluorouracil encapsulated into a chitosan-based matrix were prepared by in situ hydrogelation with 3,7-dimethyl-2,6-octadienal. The formulations were investigated from structural and morphological aspec ...
This research presents a mathematical formulation for optimizing integration of complex industrial systems from the level of unit operations to processes, entire plants, and finally to considering industrial symbiosis opportunities between plants. The fram ...
Two formulations embedding diclofenac sodium salt into a chitosan hydrogel matrix with different crosslinking degree were prepared by in situ hydrogelation. The formulations were investigated by polarized light microscopy and scanning electron microscopy, ...
A series of three formulations were prepared in view of experimental and theoretical investigation of their drug release potential. The morphology of the film formulations, in terms of distribution of drug into the polymeric matrix and the nature of the dr ...
Abstract of the invention: The present invention relates to new agents useful for stimulating release of lactate by astrocytes. The invention further relates to methods of preparation, formulations and therapeutic uses of those agents, notably for the prev ...
Amorphous solid dispersion (ASD) is one of the most promising enabling formulations featuring significant water solubility and bioavailability enhancements for biopharmaceutical classification system (BCS) class II and IV drugs. An accurate thermodynamic u ...
The SIR (‘susceptible-infectious-recovered’) formulation is used to uncover the generic spread mechanisms observed by COVID-19 dynamics globally, especially in the early phases of infectious spread. During this early period, potential controls were not eff ...
The paper describes the formulation and application of an Optimal Power Flow (OPF)-driven Under Frequency Load Shedding (UFLS) scheme in low-inertia power grids hosting large-scale battery energy storage systems. Thanks to the accurate prediction of the sy ...
Modeling dislocation multiplication due to interaction and reactions on a mesoscopic scale is an important task for the physically meaningful description of stage II hardening in face centered cubic crystalline materials. In recent Discrete Dislocation Dyn ...