Concept

Institute of Molecular Biotechnology

Résumé

The Institute of Molecular Biotechnology (IMBA) is an independent biomedical research organisation founded by the Austrian Academy of Sciences in cooperation with the pharmaceutical company Boehringer Ingelheim. The institute employs around 250 people from over 40 countries, who perform basic research. IMBA is located at the Vienna BioCenter (VBC) and shares facilities and scientific training programs with the Gregor Mendel Institute of Molecular Plant Biology (GMI) of the Austrian Academy of Sciences and the Research Institute of Molecular Pathology (IMP), the basic research center of Boehringer Ingelheim. The research at IMBA aims to understand the fundamental molecular biological processes underlying the 3D architecture of genomes, the functions of small RNAs, and the in vitro reconstitution from stem cells of whole organs and embryos. The institute comprises 15 research groups (as of December 2022): Stefan Ameres (adjunct group): Mechanism and biology of RNA silencing. Developer of the SLAMseq technology. Julius Brennecke: Transposon silencing & heterochromatin formation by small RNAs. Pioneer in the discovery of the piRNA/Piwi pathway. Alejandro Burga: Molecular determinants of biological idiosyncrasy. Ulrich Elling: Functional genomics in embryonic stem cells. Developer of Haplobank. Daniel Gerlich: Assembly and function of the cell division machinery. Anton Goloborodko: Theoretical models of chromosome structure. Sofia Grade: Mechanisms of plasticity after brain injury. Joanna Jachowicz: Dark genome in early mammalian development. Jürgen Knoblich: Brain development and disease. Developer of the cerebral organoid. Bon-Kyoung Koo: Homeostatic regulation of adult stem cells. Pioneer in adult stem cell organoids. Sasha Mendjan: Molecular control of human organogenesis. Developer of the human cardiac organoid. Josef Penninger: Modeling human disease. Nicolas Rivron: Synthetic development. Developer of the blastoid, a complete embryo model. Shambaditya Saha: Macromolecular phase separation in germ cell fate.

Source officielle

https://en.wikipedia.org/wiki/Institute_of_Molecular_Biotechnology

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