Publications associées (12)

Enhancing Consolidation of a New Temporal Motor Skill by Cerebellar Noninvasive Stimulation

Friedhelm Christoph Hummel, Maximilian Jonas Wessel

Cerebellar transcranial direct current stimulation (tDCS) has the potential to modulate cerebellar outputs and visuomotor adaptation. The cerebellum plays a pivotal role in the acquisition and control of skilled hand movements, especially its temporal aspe ...
Oxford University Press2016

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

Gioele La Manno, Jesper Ryge

Understanding human embryonic ventral midbrain is of major interest for Parkinson's disease. However, the cell types, their gene expression dynamics, and their relationship to commonly used rodent models remain to be defined. We performed single-cell RNA s ...
2016

Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF

Patrick Aebischer

In spite of partial success in treating Parkinson's disease by using ectopically placed grafts of dopamine-producing cells, restoration of the original neuroanatomical circuits, if possible, might work better. Previous evidence of normal anatomic projectio ...
2009

Notch1 is required for neuronal and glial differentiation in the cerebellum

Freddy Radtke, Michel Aguet

The mechanisms that guide progenitor cell fate and differentiation in the vertebrate central nervous system (CNS) are poorly understood. Gain-of-function experiments suggest that Notch signaling is involved in the early stages of mammalian neurogenesis. On ...
2002

Patterning signals acting in the spinal cord override the organizing activity of the isthmus

Anne Grapin-Botton

The regionalization of the neural tube along the anteroposterior axis is established through the action of patterning signals from the endo-mesoderm including the organizer. These signals set up a pre-pattern which is subsequently refined through local pat ...
1999

Defined concentrations of a posteriorizing signal are critical for MafB/Kreisler segmental expression in the hindbrain

Anne Grapin-Botton

It has been shown by using the quail/chick chimera system that Hox gene expression in the hindbrain is influenced by positional signals arising from the environment. In order to decipher the pathway that leads to Hox gene induction, we have investigated wh ...
1998

Determination of the identity of the derivatives of the cephalic neural crest: incompatibility between Hox gene expression and lower jaw development

Anne Grapin-Botton

In addition to pigment cells, and neural and endocrine derivatives, the neural crest is characterized by its ability to yield mesenchymal cells. In amniotes, this property is restricted to the cephalic region from the mid-diencephalon to the end of rhombom ...
1998

[Genetic control of rhombencephalon development by Hox genes studied in bird embryo by the quail-chick chimera method]

Anne Grapin-Botton

The rhombencephalic neural tube is transiently segmented along the anteroposterior axis into 8 rhombomeres. Each rhombomere, as well as its derived neural crest cells, is characterized by the expression of a specific set of Hox genes which constitute its H ...
1997

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