Concept
Opiacé
Publications associées (10)
Toxic Effects of Koumine on the Early-Life Development Stage of Zebrafish
Koumine is one of the most abundant alkaloids found in Gelsemium elegans, and it has a wide range of pharmacological effects including antitumor, anti-inflammatory, analgesic treatment effects, and antianxiety. However, its high toxicity and unclear mechan ...
Basel2023A Stand-Alone Augmented Reality Intervention for Chronic Pain using Embodied Systolic Stimulation
Andrea Serino, Robert Leeb, Oliver Alan Kannape, Skander Mensi, Sylvain Cardin, Fabien Bourban, Alexis Dorier
Chronic pain presents a tremendous personal, societal, and financial burden. Treatment options are often limited to managing symptoms as opposed to treating the causes, and the consequences of pharmacological treatments can be immensely harmful as evidence ...
IEEE2023Cognitive neuroprosthetics for investigating and restoring body perception
Our brain constantly receives and integrates a flow of multisensory bodily inputs that are responsible for the way our body is represented and consciously experienced. However, in some pathological conditions, patients might experience altered perceptions ...
EPFL2019Designing Safer Analgesics via mu-Opioid Receptor Pathways
Pain is both a major clinical and economic problem, affecting more people than diabetes, heart disease, and cancer combined. While a variety of prescribed or over-the-counter (OTC) medications are available for pain management, opioid medications, especial ...
Elsevier Science London2017Effects of the kappa opioid receptor antagonist MR-2266-BS on the acquisition of ethanol preference
Using a paradigm by which rats forced to drink a weak ethanol solution (2.5% w/v) (conditioning session) develop ethanol preference in consecutive retention testing days, the effects of the administration of the kappa opioid antagonist MR-2266-BS, prior to ...
1990Involvement of kappa type opioids on ethanol drinking
The effects of the administration of the kappa agonist dynorphin1-17 and/or the kappa antagonist MR-2266-BS on ethanol preference was investigated using a paradigm by which rats develop alcohol preference. Administration of dynorphin shortly before or afte ...
1988Studies on the synthesis of morphine. VI. Recent progress on the biomimetic synthesis of morphine
Experiments to find a biomimetic route for synthesizing morphine are summarized. Systematic investigations on the phenolic oxidative coupling have been revised and evaluated. ...
1983