Neurone pseudo-unipolaire | EPFL Graph Search

A pseudounipolar neuron is a type of neuron which has one extension from its cell body. This type of neuron contains an axon that has split into two branches. A single process arises from the cell body and then divides into an axon and a dendrite. They develop embryologically as bipolar in shape, and are thus termed pseudounipolar instead of unipolar. A pseudounipolar neuron has one axon that projects from the cell body for relatively a very short distance, before splitting into two branches. Pseudounipolar neurons are sensory neurons that have no dendrites, the branched axon serving both functions. The peripheral branch extends from the cell body to organs in the periphery including skin, joints and muscles, and the central branch extends from the cell body to the spinal cord. The cell body of a pseudounipolar neuron is located within a dorsal root ganglion. The axon leaves the cell body (and out of the dorsal root ganglion) into the dorsal root, where it splits into two branches. The central branch goes to the dorsal columns of the spinal cord, where it forms synapses with other neurons. The peripheral branch travels through the distal dorsal root into the spinal nerve all the way until skin, joint, and muscle. Pseudounipolar neurons are found in the sensory ganglia of most cranial nerves. Specifically the: trigeminal ganglion geniculate ganglion superior ganglion of the glossopharyngeal nerve inferior ganglion of the glossopharyngeal nerve superior ganglion of the vagus nerve inferior ganglion of the vagus nerve Pseudounipolar neurons in cranial nerve sensory ganglia synapse in the main sensory trigeminal nucleus, spinal trigeminal nucleus or solitary nucleus. While the vestibulocochlear nerve has two ganglia associated with it (spiral ganglion and vestibular ganglion), both contain bipolar neurons, not pseudounipolar. mesencephalic nucleus The mesencephalic nucleus is made up of pseudounipolar neurons which migrated into the brainstem during embryological development.

Task-driven neural network models predict neural dynamics of proprioception: Neural network model weights

Alexander Mathis, Alberto Silvio Chiappa, Alessandro Marin Vargas, Axel Bisi

Proprioception tells the brain the state of the body based on distributed sensors in the body. However, the principles that govern proprioceptive processing from those distributed sensors are poorly understood. Here, we employ a task-driven neural network ...

EPFL Infoscience2024

Task-driven neural network models predict neural dynamics of proprioception

Alexander Mathis, Alberto Silvio Chiappa, Alessandro Marin Vargas, Axel Bisi

2023

CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection

Ludovic Pierre Gustave Keiser, Laura Desban

The pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) can invade the cerebrospinal fluid (CSF) and cause meningitis with devastating consequences. Whether and how sensory cells in the central nervous system (CNS) become activated during bacteri ...

CELL PRESS2023