Publications associées à Apoptose

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

Yi Zhang, Friedrich Beermann, Jie Zhang, Yuan Liu, Qian Zhang, Li Li, Ang Li, Ping Chen, Bo Zhou, Rong Wu

Autophagy is linked to cell death, yet the associated mechanisms are largely undercharacterized. We discovered that melanoma, which is generally resistant to drug-induced apoptosis, can undergo autophagic cell death with the participation of orphan nuclear ...

Nature Publishing Group2014

The anti-lymphoma activity of APO866, an inhibitor of nicotinamide adenine dinucleotide biosynthesis, is potentialized when used in combination with anti-CD20 antibody

Pierre Vogel, Somi Reddy Majjigapu, Bernard Sordat

APO866 is an inhibitor of nicotinamide adenine dinucleotide (NAD) biosynthesis that exhibits potent anti-lymphoma activity. Rituximab (RTX), an anti-CD20 antibody, kills lymphoma cells by direct apoptosis and antibody- and complement-dependent cell-mediate ...

Informa Healthcare2014

Deleterious effect of homogeneous and heterogeneous near-neutral photo-Fenton system on Escherichia coli. Comparison with photo-catalytic action of TiO2 during cell envelope disruption

César Pulgarin, Andrzej Sienkiewicz, Cristina del Socorro Lonfat

The mechanisms underlying bacterial inactivation by solar photo-Fenton at near-neutral pH have not yet been investigated in detail. In particular, no consensus exists on the bacterial inactivation mechanism under solar light enhanced by the Fenton's reagen ...

Elsevier Science Bv2014

A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

Pierre Vogel, Somi Reddy Majjigapu, Bernard Sordat

APO866, an inhibitor of NAD biosynthesis, exhibits potent antitumor properties in various malignancies. Recently, it has been shown that APO866 induces apoptosis and autophagy in human hematological cancer cells, but the role of autophagy in APO866-induced ...

Landes Bioscience2014

Immunomodulatory Roles of Lymphatic Vessels in Cancer Progression

Melody Swartz

Lymphatic vessels in the tumor microenvironment are known to foster tumor metastasis in many cancers, and they can undergo activation, hyperplasia, and lymphangiogenesis in the tumor microenvironment and in the tumor-draining lymph node. The mechanism unde ...

Amer Assoc Cancer Research2014

Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations

Liviu Vanoaica, Maike Jaworski

The immune system and iron availability are intimately linked as appropriate iron supply is needed for cell proliferation, while excess iron, as observed in hemochromatosis, may reduce subsets of lymphocytes. We have tested the effects of a ferritin H gene ...

Public Library of Science2014

PROX1 Promotes Metabolic Adaptation and Fuels Outgrowth of Wnt(high) Metastatic Colon Cancer Cells

Nadine Fournier, Mauro Delorenzi, Simone Ragusa, Stavros Milatos

The Wnt pathway is abnormally activated in the majority of colorectal cancers, and significant knowledge has been gained in understanding its role in tumor initiation. However, the mechanisms of metastatic outgrowth in colorectal cancer remain a major chal ...

Elsevier2014

Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development

Michel Aguet, Andreas Eduard Moor

Bcl9 and Bcl9l (Bcl9/9l) encode Wnt signaling components that mediate the interaction between beta-catenin and Pygopus (Pygo) via two evolutionarily conserved domains, HD1 and HD2, respectively. We generated mouse strains lacking these domains to probe the ...

Cold Spring Harbor Laboratory Press2014

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Apoptose

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

The anti-lymphoma activity of APO866, an inhibitor of nicotinamide adenine dinucleotide biosynthesis, is potentialized when used in combination with anti-CD20 antibody

Deleterious effect of homogeneous and heterogeneous near-neutral photo-Fenton system on Escherichia coli. Comparison with photo-catalytic action of TiO2 during cell envelope disruption

A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

Immunomodulatory Roles of Lymphatic Vessels in Cancer Progression

BactImAS: a platform for processing and analysis of bacterial time-lapse microscopy movies

Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations

PROX1 Promotes Metabolic Adaptation and Fuels Outgrowth of Wnt(high) Metastatic Colon Cancer Cells

Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development

Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS

Graph Chatbot

Chattez avec Graph Search

Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway

Deleterious effect of homogeneous and heterogeneous near-neutral photo-Fenton system on Escherichia coli. Comparison with photo-catalytic action of TiO2 during cell envelope disruption

The anti-lymphoma activity of APO866, an inhibitor of nicotinamide adenine dinucleotide biosynthesis, is potentialized when used in combination with anti-CD20 antibody

A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

BactImAS: a platform for processing and analysis of bacterial time-lapse microscopy movies

Immunomodulatory Roles of Lymphatic Vessels in Cancer Progression

Necroptosis Drives Motor Neuron Death in Models of Both Sporadic and Familial ALS

Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development

Conditional Deletion of Ferritin H in Mice Reduces B and T Lymphocyte Populations

PROX1 Promotes Metabolic Adaptation and Fuels Outgrowth of Wnt(high) Metastatic Colon Cancer Cells