Publications associées à Greffe de pancréas

Longitudinal incremental propensity score interventions for limited resource settings

Many real‐life treatments are of limited supply and cannot be provided to all individuals in the population. For example, patients on the liver transplant waiting list usually cannot be assigned a liver transplant immediately at the time they reach highest ...

2023

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Jacques Fellay, Christian Axel Wandall Thorball

Type 2 diabetes mellitus (T2DM) can be multifactorial where both genetics and environmental factors play a role. We aimed to investigate the use of polygenic risk scores (PRS) in the prediction of pre-transplant T2DM and post-transplant diabetes mellitus ( ...

Lausanne2023

Islet Encapsulation: New Developments for the Treatment of Type 1 Diabetes

Sandrine Gerber, Qixing Zhang, Yi Wang, Léo Bühler

Islet transplantation is a promising approach for the treatment of type 1 diabetes (T1D). Currently, clinical islet transplantation is limited by allo - and autoimmunity that may cause partial or complete loss of islet function within a short period of tim ...

2022

Assessment of Stiffness of Large to Small Arteries in Multistage Renal Disease Model: A Numerical Study

Nikolaos Stergiopoulos, Vasiliki Bikia, Patrick Segers

Arterial stiffness (AS), as assessed via pulse wave velocity (PWV), is a major biomarker for cardiovascular risk assessment in patients with chronic kidney disease (CKD). However, the mechanisms responsible for the changes in PWV in the presence of kidney ...

FRONTIERS MEDIA SA2022

Oxygen-rich Environment Ameliorates Cell Therapy Outcomes of Cardiac Progenitor Cells for Myocardial Infarction

Philippe Renaud, Shahin Bonakdar, Fatemeh Navaee, Leila Montazeri, Hassan Ansari

To some extent, cell therapy for myocardial infarction (MI) has supported the idea of cardiac repair; however, further optimizations are inevitable. Combined approaches that comprise suitable cell sources and supporting molecules considerably improved its ...

2021

Causal inference with limited resources: proportionally-representative interventions

Mats Julius Stensrud, Aaron Leor Sarvet

Investigators often evaluate treatment effects by considering settings in which all individuals are assigned a treatment of interest, assuming that an unlimited number of treatment units are available. However, many real-life treatments are of limited supp ...

2020

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Loïc Dayon, Sofia Moco, Andreas Wiederkehr, Isabelle Chareyron

Aims/hypothesis In islets from individuals with type 2 diabetes and in islets exposed to chronic elevated glucose, mitochondrial energy metabolism is impaired. Here, we studied early metabolic changes and mitochondrial adaptations in human beta cells durin ...

2020

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice

Jeffrey Alan Hubbell, Mikaël Martino, Alice Anna Tomei

With a view toward reduction of graft loss, we explored pancreatic islet transplantation within fibrin matrices rendered pro-angiogenic by incorporation of minimal doses of vascular endothelial growth factor-A165 and platelet-derived growth factor-BB prese ...

Wiley-Blackwell2015

REST represses a subset of the pancreatic endocrine differentiation program

Anne Grapin-Botton, Yung Hae Kim

To contribute to devise successful beta-cell differentiation strategies for the cure of Type 1 diabetes we sought to uncover barriers that restrict endocrine fate acquisition by studying the role of the transcriptional repressor REST in the developing panc ...

Academic Press Inc Elsevier Science2015

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Greffe de pancréas

Longitudinal incremental propensity score interventions for limited resource settings

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Islet Encapsulation: New Developments for the Treatment of Type 1 Diabetes

Assessment of Stiffness of Large to Small Arteries in Multistage Renal Disease Model: A Numerical Study

Oxygen-rich Environment Ameliorates Cell Therapy Outcomes of Cardiac Progenitor Cells for Myocardial Infarction

Causal inference with limited resources: proportionally-representative interventions

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Pancreatic islet cells isolation and transplantation into the bone marrow

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice

REST represses a subset of the pancreatic endocrine differentiation program

Graph Chatbot

Chattez avec Graph Search

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Longitudinal incremental propensity score interventions for limited resource settings

Islet Encapsulation: New Developments for the Treatment of Type 1 Diabetes

Assessment of Stiffness of Large to Small Arteries in Multistage Renal Disease Model: A Numerical Study

Oxygen-rich Environment Ameliorates Cell Therapy Outcomes of Cardiac Progenitor Cells for Myocardial Infarction

Causal inference with limited resources: proportionally-representative interventions

Augmented mitochondrial energy metabolism is an early response to chronic glucose stress in human pancreatic beta cells

Pancreatic islet cells isolation and transplantation into the bone marrow

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice

REST represses a subset of the pancreatic endocrine differentiation program