Concept
Poliomyélite
Publications associées (17)
Concerted Activity of IgG1 Antibodies and IL-4/IL-25-Dependent Effector Cells Trap Helminth Larvae in the Tissues following Vaccination with Defined Secreted Antigens, Providing Sterile Immunity to Challenge Infection
Nicola Harris, Julia Esser-von Bieren
Over 25% of the world's population are infected with helminth parasites, the majority of which colonise the gastrointestinal tract. However, no vaccine is yet available for human use, and mechanisms of protective immunity remain unclear. In the mouse model ...
Public Library of Science2015Endoplasmic Reticulum Stress Is Important for the Manifestations of alpha-Synucleinopathy In Vivo
Bernard Schneider, Ying Liu, Philippe Guillaume Coune
Accumulation of misfolded alpha-synuclein (alpha S) is mechanistically linked to neurodegeneration in Parkinson's disease (PD) and other alpha-synucleinopathies. However, how alpha S causes neurodegeneration is unresolved. Because cellular accumulation of ...
Society for Neuroscience2012AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway
A dominant mutation in the gene coding for the vesicle-associated membrane protein-associated protein B (VAPB) was associated with amyotrophic lateral sclerosis, a fatal paralytic disorder characterized by the selective loss of motoneurons in the brain and ...
Wiley-Blackwell2010HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C
Jacques Fellay, Amalio Telenti
A variant 35 kb upstream of the HLA-C gene (-35C/T) was previously shown to associate with HLA-C mRNA expression level and steady-state plasma HIV RNA levels. We genotyped this variant in 1,698 patients of European ancestry with HIV. Individuals with known ...
2009Synthesis and characterisation of some water soluble ruthenium(II)-arene complexes and an investigation of their antibiotic and antiviral properties
Paul Joseph Dyson, Claire Samantha Allardyce
The water soluble ruthenium-p-cymene complexes Ru(eta(6)-p-cymene)X-2 (X = Cl, Br, I or NCS), [Ru(eta(6)-p-cymene)X-2(pta)] (X=Cl, Br, I, or NCS; pta=1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane) and the tetraruthenium cluster [H4Ru4(eta(6)-p-benzene ...
2003Prediction of the disinfection and oxidation efficiency of full-scale ozone reactors
The efficiency of a two-step ozonation with regard to disinfection and oxidation of micropollutants; was assessed for a river-water treatment plant (Limmat River, Zurich, Switzerland). The assessment was based on laboratory experiments to estimate transien ...
2003Modalities of interleukin-7-induced human immunodeficiency virus permissiveness in quiescent T lymphocytes
The metabolic and cell cycle status of primary T lymphocytes conditions their susceptibility to human immunodeficiency virus (HIV) and HIV-derived vectors. While in fully quiescent T lymphocytes the reverse transcription and nuclear import of these retroel ...
2002