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While the bulk structure of a material determines its mechanical properties, its surface plays a key role when interactions with the environment are important. Nowadays materials in bio- and nanotechnology are required to possess very complex functionaliti ...
In clinical situations, bone defects are often located at load bearing sites. Tissue engineering scaffolds are future bone substitutes and hence they will be subjected to mechanical stimulation. The goal of this study was to test if cyclic loading can be u ...
An obvious means to improve the fixation of a cancellous bone screw is to augment the surrounding bone with cement. Previous studies have shown that bone augmentation with Calcium Phosphate (CaP) cement significantly improves screw fixation. Nevertheless, ...
Reversed shoulder prostheses are used for the treatment for glenohumeral arthritis associated to rotator cuff muscle deficiency. The glenoid component is fixed with peripheral screws, which provide the primary stability that is crucial for the long-term os ...
Previous studies support resorbable biocomposites made of poly L-lactic acid (PLA) and β-tricalcium phosphate (TCP) produced by supercritical gas foaming as a suitable scaffold for tissue engineering. The present study was undertaken to demonstrate the bio ...
Tissue engineering scaffolds are porous structures that allow bone cells to reside and produce bone. This process involves migration and differentiation of mesenchymal stromal cells and production of cartilage and bone by chondrocytes and osteoblasts, whic ...
One of the recently developed methods for measuring mechanical properties of complex structures, like bone, is back-calculation using finite element models. This has been achieved due to emergence of high computing powers and high resolution CT scanners in ...
Bone is an amazing material evolved by nature to elegantly balance structural and metabolic needs in the body. Bone health is an integral part of overall health, but our lack of understanding of the ultrastructure of healthy bone precludes us from knowing ...
The aim of this study is to compare the difference in µ-motion between a custom stem implant and a sps standard stem and assess the importance of patient specificity. A surgeon would implant 3 sps-standar stems and 3 custom stems in 6 cadaveric femurs. The ...
Biomechanics may be considered as central in the development of bone tissue engineering. The initial mechanical aspects are essential to the outcome of a functional tissue engineering approach, so are aspects of interface micromotion, bone ingrowths inside ...