Publications associées à Mineralized tissues

Additive Manufacturing of Bioinspired Mineral-Based Composites

Biominerals are used by natural organisms for example as structural supports and optical sensors. They are produced from a limited number of elements and under ambient conditions. Nevertheless, they often possess excellent mechanical properties and sometim ...

EPFL2024

Controlling the Microstructure and Composition of 3D Printed Soft Load-Bearing Hydrogels

Matteo Hirsch

Hydrogels are among the first materials expressly designed for their use in biomedicine. However, state-of-the-art applications of hydrogels are severely limited because they are typically either too soft or too brittle such that they cannot bear significa ...

EPFL2023

Micromechanically inspired investigation of cemented granular materials: part I-from X-ray micro tomography to measurable model variables

Gioacchino Viggiani, Edward Carlo Giorgio Andò

Cemented granular materials are abundant in nature and are often artificially produced. Their macroscopic behaviour is driven by small-scale material processes, which are generally classified as: grain breakage, cement damage and fragment rearrangement. Th ...

SPRINGER HEIDELBERG2022

Deformation and Fracture of Tough Microstructured Hydrogels

Michael David Kessler

Many natural materials are structured on different length scales. This structuring often leads to an intricate interplay between soft and stiff components, which significantly improves the fracture toughness of these materials. A class of soft material tha ...

EPFL2022

The effects of time-restricted eating and weight loss on bone metabolism and health: a 6-month randomized controlled trial

Nicholas Edward Phillips, Alexandra Hemmer

Objective This study explored the impact of time-restricted eating (TRE) versus standard dietary advice (SDA) on bone health. Methods Adults with >= 1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food p ...

WILEY2022

Microfluidic study in a meter-long reactive path reveals how the medium’s structural heterogeneity shapes MICP-induced biocementation

Lyesse Laloui, Dimitrios Terzis, Ariadni Elmaloglou

Microbially induced calcium carbonate (CaCO3) precipitation (MICP) is one of the major sustainable alternatives to the artificial cementation of granular media. MICP consists of injecting the soil with bacterial- and calcium-rich solutions sequentially to ...

Nature Research2022

Intrinsically High Capacity of Animal Cells From a Symbiotic Cnidarian to Deal With Pro-Oxidative Conditions

Gaëlle Delphine Toullec

The cnidarian-dinoflagellate symbiosis is a mutualistic intracellular association based on the photosynthetic activity of the endosymbiont. This relationship involves significant constraints and requires co-evolution processes, such as an extensive capacit ...

FRONTIERS MEDIA SA2022

Multiscale light-sheet organoid imaging framework

Petr Strnad, Andrea Boni, Raphaël Ortiz

Live imaging of organoid growth remains a challenge: it requires long-term imaging of several samples simultaneously and dedicated analysis pipelines. Here the authors report an experimental and image processing framework to turn long-term light-sheet imag ...

Nature Portfolio2022

Reinforcing hydrogels with in situ formed amorphous CaCO3

Esther Amstad, Matteo Hirsch, Ran Zhao, Tianyu Yuan, Huachuan Du, Michael David Kessler

Hydrogels are often employed for tissue engineering and moistening applications. However, they are rarely used for load-bearing purposes because of their limited stiffness and the stiffness-toughness compromise inherent to them. By contrast, nature uses hy ...

ROYAL SOC CHEMISTRY2022

Microtensile failure mechanisms in lamellar bone: Influence of fibrillar orientation, specimen size and hydration

Johann Michler, Daniele Casari, Tatiana Kochetkova

A mechanistic understanding of bone fracture is indispensable for developing improved fracture risk assessment in clinics. Since bone is a hierarchically structured material, gaining such knowledge requires analysis at multiple length scales. Here, the ten ...

ELSEVIER SCI LTD2021