Publications associées à Puce à ADN

Achieving high hybridization density at DNA biosensor surfaces using branched spacer and click chemistry

Sandrine Gerber, Mounir Driss Mensi, Perrine Agnes Edith Robin, Alireza Kavand, Lucas Mayoraz

The COVID-19 pandemic has highlighted the necessity to develop fast, highly sensitive and selective virus detection methods. Surface-based DNA-biosensors are interesting candidates for this purpose. Functionalization of solid substrates with DNA must be pr ...

2023

Efficient and sensitive profiling of RNA–protein interactions using TLC-CLIP

Didier Trono, Julien Léonard Duc, Christina Ernst

RNA-binding proteins are instrumental for post-transcriptional gene regulation, controlling all aspects throughout the lifecycle of RNA molecules. However, transcriptome-wide methods to profile RNA-protein interactions in vivo remain technically challengin ...

2023

Tailoring the Hybridization Density of DNA Biosensors through Tunable Surface Functionalization

Sandrine Gerber, Mounir Driss Mensi, Perrine Agnes Edith Robin, Pauline Skigin, Lucas Mayoraz

DNA biosensors are promising candidates for the development of point-of-care diagnosis methods. They can be inserted in microfluidic platforms, are often non-expensive, and can be produced for a variety of targeted analytes. However, their development face ...

2023

A field-capable rapid plant DNA extraction protocol using microneedle patches for botanical surveying and monitoring

Sebastian Maerkl, Nicolas Rémi Adam, Jonathan Selz

PremiseA novel protocol for rapid plant DNA extraction using microneedles is proposed, which supports botanic surveys, taxonomy, and systematics. This protocol can be conducted in the field with limited laboratory skills and equipment. The protocol is vali ...

WILEY2023

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Sebastian Maerkl, Shiyu Cheng, Hon Ming Andrew Yip, Evan James Olson, Michael Andrew Crone

Cells cope with and adapt to ever-changing environmental conditions. Sophisticated regulatory networks allow cells to adjust to these fluctuating environments. One such archetypal system is the Saccharomyces cerevisiae Pho regulon. When external inorganic ...

Washington2023

Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation

Martinus Gijs, Thomas Lehnert, Lin Sun

DNA fragmentation is an essential process in developing genetic sequencing strategies, genetic research, as well as for the diagnosis of diseases with a genetic signature like cancer. Efficient on-chip DNA fragmentation protocols would be beneficial to pro ...

ROYAL SOC CHEMISTRY2022

Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations

Jacques Fellay, Zhi Ming Xu, Sina Rüeger

Genome-wide association studies rely on the statistical inference of untyped variants, called imputation, to increase the coverage of genotyping arrays. However, the results are often suboptimal in populations underrepresented in existing reference panels ...

San Francisco2022

DNA-Liposome Hybrid Carriers for Triggered Cargo Release

Diana Kornelia Morzy

The design of simple and versatile synthetic routes to accomplish triggered-release properties in carriers is of particular interest for drug delivery purposes. In this context, the programmability and adaptability of DNA nanoarchitectures in combination w ...

AMER CHEMICAL SOC2022

Directed evolution of DNA-wrapped single-walled carbon nanotube complexes for optical sensing

Benjamin Paul Johanès Gabriel Lambert

Single-walled carbon nanotubes (SWCNTs) have garnered significant interest for their applications in optical biosensing. SWCNTs exhibit a sensitive and photostable fluorescence in the near-infrared (NIR) range, allowing for the continuous monitoring of tar ...

EPFL2021

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Puce à ADN

Achieving high hybridization density at DNA biosensor surfaces using branched spacer and click chemistry

Development of multiplexed single-molecule imaging techniques to study chromatin invasion dynamics of chromatin effector proteins

Efficient and sensitive profiling of RNA–protein interactions using TLC-CLIP

Tailoring the Hybridization Density of DNA Biosensors through Tunable Surface Functionalization

A field-capable rapid plant DNA extraction protocol using microneedle patches for botanical surveying and monitoring

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation

Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations

DNA-Liposome Hybrid Carriers for Triggered Cargo Release

Directed evolution of DNA-wrapped single-walled carbon nanotube complexes for optical sensing

Graph Chatbot

Chattez avec Graph Search

Achieving high hybridization density at DNA biosensor surfaces using branched spacer and click chemistry

Development of multiplexed single-molecule imaging techniques to study chromatin invasion dynamics of chromatin effector proteins

Efficient and sensitive profiling of RNA–protein interactions using TLC-CLIP

Tailoring the Hybridization Density of DNA Biosensors through Tunable Surface Functionalization

A field-capable rapid plant DNA extraction protocol using microneedle patches for botanical surveying and monitoring

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Bubble-enhanced ultrasonic microfluidic chip for rapid DNA fragmentation

Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations

DNA-Liposome Hybrid Carriers for Triggered Cargo Release

Directed evolution of DNA-wrapped single-walled carbon nanotube complexes for optical sensing