Concept

Médecine personnalisée

Publications associées (125)

Topology predicts long-term functional outcome in early psychosis

Kathryn Hess Bellwald, Kim Do, Martina Scolamiero

Early intervention in psychosis is crucial to improving patient response to treatment and the functional deficits that critically affect their long-term quality of life. Stratification tools are needed to personalize functional deficit prevention strategie ...

2020

Microfluidic systems for cancer diagnostics

Sebastian Maerkl, Jose Luis Garcia Cordero

Although not employed in the clinic as of yet, microfluidic systems are likely to become a key technology for cancer diagnostics and prognosis. Microfluidic devices have been developed for the analysis of various biomarkers including circulating tumor cell ...

CURRENT BIOLOGY LTD2020

Value Creation in Precision Medicine: Acknowledging the Need to Devise New Ways to Measure. The Value of Healthcare

Anjali Devi Vanapilli Nursimulu

Precision medicine holds the promise of bringing the right treatment to the right patient at the right time with the upside of reduced undesirable effects. But the impact on healthcare costs are not clear. While targeting of conventional drugs through prec ...

International Risk Governance Center (IRGC)2019

Real-world gait speed estimation using wrist sensor: A personalized approach

Kamiar Aminian, Hooman Dejnabadi, Abolfazl Soltani, Martin Savary

Gait speed is an important parameter to characterize people's daily mobility. For real-world speed measurement, inertial sensors or Global Navigation Satellite System (GNSS) can be used on wrist, possibly integrated in a wristwatch. However, power consumpt ...

2019

Microfluidics-assisted multiplexed biomarker detection for in situ mapping of immune cells in tumor sections

Martinus Gijs, Daniel Migliozzi, Diego Gabriel Dupouy, Benjamin Pelz

Because of the close interaction between tumors and the immune system, immunotherapies are nowadays considered as the most promising treatment against cancer. In order to define the diagnosis and the subsequent therapy, crucial information about the immune ...

2019

Integrated Nanophotonic Biosensors for Point-of Care Diagnostics and Bioanalytical Applications

Hatice Altug, Xiaokang Li, Filiz Yesilköy, Alexander Belushkin, Yasaman Jahani

In an effort to address the requirements of next-generation healthcare systems, including personalized medicine, point-of-care diagnostics, and global health surveillance, I will introduce imaging-based portable nanoplasmonic biosensors integrated with mic ...

IEEE2019

Control theory in biology and medicine: Introduction to the special issue

Auke Ijspeert

From September-December 2017, the Mathematical Biosciences Institute at Ohio State University hosted a series of workshops on control theory in biology and medicine, including workshops on control and modulation of neuronal and motor systems, control of ce ...

SPRINGER2019

Microfluidics as an Enabling Technology for Personalized Cancer Therapy

Christoph Merten

Tailoring patient‐specific treatments for cancer is necessary in order to achieve optimal results but requires new diagnostic approaches at affordable prices. Microfluidics has immense potential to provide solutions for this, as it enables the processing o ...

2019

Functionalization of second harmonic generation nanoparticles for theranostic applications

Jérémy Vuilleumier

Nowadays, cancer is one of the leading causes of death in developed countries. The actual medical tools to detect cancer at early stage suffer to their low sensitivity. The design of multimodal nanodevices for in vivo imaging offers the perspective of canc ...

EPFL2019

Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis

Jacques Fellay, Alessandro Borghesi

Computational analyses of human patient exomes aim to filter out as many nonpathogenic genetic variants (NPVs) as possible, without removing the true disease-causing mutations. This involves comparing the patient's exome with public databases to remove rep ...

NATL ACAD SCIENCES2019

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